AIMC Topic: Aged, 80 and over

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Predicting Inpatient Medication Orders From Electronic Health Record Data.

Clinical pharmacology and therapeutics
In a general inpatient population, we predicted patient-specific medication orders based on structured information in the electronic health record (EHR). Data on over three million medication orders from an academic medical center were used to train ...

Abdominal multi-organ auto-segmentation using 3D-patch-based deep convolutional neural network.

Scientific reports
Segmentation of normal organs is a critical and time-consuming process in radiotherapy. Auto-segmentation of abdominal organs has been made possible by the advent of the convolutional neural network. We utilized the U-Net, a 3D-patch-based convolutio...

Automatic diagnosis of the 12-lead ECG using a deep neural network.

Nature communications
The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has re...

Role of Deep Learning-Quantified Hyperreflective Foci for the Prediction of Geographic Atrophy Progression.

American journal of ophthalmology
PURPOSE: To quantitatively measure hyperreflective foci (HRF) during the progression of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) using deep learning (DL) and investigate the association with local and global growth ...

Deep learning prediction of falls among nursing home residents with Alzheimer's disease.

Geriatrics & gerontology international
AIM: This study aimed to use a convolutional neural network (CNN) to investigate the associations between the time of falling and multiple complicating factors, including age, dementia severity, lower extremity strength and physical function, among n...

A Machine Learning Approach for High-Dimensional Time-to-Event Prediction With Application to Immunogenicity of Biotherapies in the ABIRISK Cohort.

Frontiers in immunology
Predicting immunogenicity for biotherapies using patient and drug-related factors represents nowadays a challenging issue. With the growing ability to collect massive amount of data, machine learning algorithms can provide efficient predictive tools....

Opening the black box of artificial intelligence for clinical decision support: A study predicting stroke outcome.

PloS one
State-of-the-art machine learning (ML) artificial intelligence methods are increasingly leveraged in clinical predictive modeling to provide clinical decision support systems to physicians. Modern ML approaches such as artificial neural networks (ANN...

Deep learning-based cancer survival prognosis from RNA-seq data: approaches and evaluations.

BMC medical genomics
BACKGROUND: Recent advances in kernel-based Deep Learning models have introduced a new era in medical research. Originally designed for pattern recognition and image processing, Deep Learning models are now applied to survival prognosis of cancer pat...

Automatic detection of cortical arousals in sleep and their contribution to daytime sleepiness.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Significant interscorer variability is found in manual scoring of arousals in polysomnographic recordings (PSGs). We propose a fully automatic method, the Multimodal Arousal Detector (MAD), for detecting arousals.

Rapid Screening of Thyroid Dysfunction Using Raman Spectroscopy Combined with an Improved Support Vector Machine.

Applied spectroscopy
This study aimed to screen for thyroid dysfunction using Raman spectroscopy combined with an improved support vector machine (SVM). In spectral analysis, in order to further improve the classification accuracy of the SVM algorithm model, a genetic pa...