AIMC Topic: Aged
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Development and validation of a predictive model for refracture risk in elderly individuals with osteoporotic vertebral compression fracture: a retrospective study in China.
Aging clinical and experimental research
May 26, 2025
BACKGROUND: The rising incidence of refractures and associated adverse outcomes among individuals with osteoporotic vertebral compression fractures has gained significant attention. Identifying refracture risk is crucial for implementing effective pr...
Retrospective cohort study of infection and risk stratification using 6-year UBT data.
Frontiers in public health
May 26, 2025
BACKGROUND: () infection is a major global health concern, linked to gastric cancer and metabolic disorders. Despite its widespread prevalence, accurate risk stratification remains challenging. This study aims to develop a machine learning (ML)-base...
Characterising physical activity patterns in community-dwelling older adults using digital phenotyping: a 2-week observational study protocol.
BMJ open
May 24, 2025
INTRODUCTION: Physical activity (PA) is crucial for older adults' well-being and mitigating health risks. Encouraging active lifestyles requires a deeper understanding of the factors influencing PA, which conventional approaches often overlook by ass...
Analysis of the heterogeneous treatment effect of vasoactive drug dosage and time on hospital mortality across different sepsis phenotypes: a retrospective cohort study.
European journal of medical research
May 24, 2025
BACKGROUND: The heterogeneity of sepsis poses challenges for the individualized treatment of vasoactive drugs.
Development of a non-contrast CT-based radiomics nomogram for early prediction of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage.
BMC medical imaging
May 23, 2025
BACKGROUNDS: Delayed cerebral ischemia (DCI) is a significant complication following aneurysmal subarachnoid hemorrhage (aSAH), leading to poor prognosis and high mortality. This study developed a non-contrast CT (NCCT)-based radiomics nomogram for e...
Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.
Scientific reports
May 23, 2025
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...
Development and validation of a multi-omics hemorrhagic transformation model based on hyperattenuated imaging markers following mechanical thrombectomy.
Scientific reports
May 23, 2025
This study aimed to develop a predictive model integrating clinical, radiomics, and deep learning (DL) features of hyperattenuated imaging markers (HIM) from computed tomography scans immediately following mechanical thrombectomy (MT) to predict hemo...
Leveraging Digital Twins for Stratification of Patients with Breast Cancer and Treatment Optimization in Geriatric Oncology: Multivariate Clustering Analysis.
JMIR cancer
May 23, 2025
BACKGROUND: Defining optimal adjuvant therapeutic strategies for older adult patients with breast cancer remains a challenge, given that this population is often overlooked and underserved in clinical research and decision-making tools.
Association between fibrinogen levels and prognosis in critically bleeding patients: exploration of the optimal therapeutic threshold.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
May 23, 2025
BACKGROUND: Severe bleeding is a leading cause of ICU admission and mortality. Fibrinogen plays a crucial role in prognosis, yet optimal thresholds and supplementation targets remain unclear.
Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.
Frontiers in public health
May 23, 2025
BACKGROUND: This study investigated the cost-effectiveness and clinical impact of the 3E model (education, empowerment, and economy) in diabetes management using advanced machine learning techniques.
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