AIMC Topic: Aged

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Automated AI detection of thoracic aortic dissection on CT imaging.

European radiology experimental
BACKGROUND: Aortic dissection (AD) is a life-threatening condition. We developed an artificial intelligence (AI) algorithm capable of robust, accurate, and automated AD detection and sub-classification.

Gaining Brain Insights by Tapping into the Black Box: Linking Structural MRI Features to Age and Cognition using Shapley-Based Interpretation Methods.

Neuroinformatics
Global interpretability in machine learning holds great potential for extracting meaningful insights from neuroimaging data to improve our understanding of brain function. Although various approaches exist to identify key contributing features at bot...

A machine learning approach for predicting 72-hour mortality of hypothermic patients only using non-invasive parameters: A multi-center retrospective cohort study.

PloS one
OBJECTIVES: Accurately predicting the mortality risk of hypothermia patients is crucial for clinical decision-making, offering ample time for physicians to intervene. However, existing methods are invasive and difficult to implement in pre-hospital s...

Effects of iron repletion on brain iron content, myelination, neural network activation, and cognition.

JCI insight
BACKGROUNDBlood donation increases the risk of iron deficiency, but its effect on brain iron, myelination, and neurocognition remains unclear.METHODSThis ancillary study enrolled 67 iron-deficient blood donors, 19-73 years of age, participating in a ...

Aging as an active player in Alzheimer's disease classification: Insights from feature selection in BrainAge models.

NeuroImage
BACKGROUND: BrainAge models estimate the biological age of the brain using neuroimaging or clinical features, making them promising tools for studying neurodegenerative diseases like Alzheimer's disease. However, the reliance of BrainAge models on ne...

Clinical application of 3D reconstruction and accurate volume measurement of white matter in patients with cognitive dysfunction.

Scientific reports
To quantitatively measure the volume of white matter hyperintensities (WMHs) in different parts of the brain in patients with different types of cognitive function and analyze the relationship between WMH volume and cognitive function to obtain a thr...

Visuospatial performance and its neural substrates in Dementia with Lewy Bodies during a pointing task.

Scientific reports
Dementia with Lewy Bodies (DLB) is characterized by motor and cognitive deficits that often overlap with other neurodegenerative disorders, complicating its diagnosis. This study combined linear mixed-effects modeling and machine learning to investig...

Multidimensional factors of health-related quality of life in parkinson's disease using ensemble learning and network analysis.

Scientific reports
Parkinson's disease (PD) causes motor, non-motor, and mental health challenges that significantly impact health-related quality of life (HRQoL); however, previous studies relied on subjective assessments. Several factors are associated with poor HRQo...

Multimodal prediction of metastatic relapse using federated deep learning in soft-tissue sarcoma with a complex genomic profile.

Scientific reports
Soft Tissue sarcomas (STS) are a group of heterogeneous and complex diseases where being able to predict the appearance of metastases is key to inform clinical decisions, especially the prescription of adjuvant chemotherapy. We developed SarcNet: a m...