BACKGROUND AND OBJECTIVES: Early and cost-effective identification of amyloid positivity is crucial for Alzheimer's disease (AD) diagnosis. While amyloid PET is the gold standard, plasma biomarkers such as phosphorylated tau 217 (pTau217) provide a p...
BACKGROUND: Antipsychotic medications are frequently prescribed to older residents of long-term care facilities (LTCFs) despite their limited efficacy and considerable safety risks. While discontinuation of these drugs might help reduce their associa...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Aug 20, 2025
PURPOSE: This study aims to explore the role of patient-reported cancer care coordination in explaining depression among head and neck (HNC) cancer survivors.
Prostate cancer (PCa) diagnosis remains challenging due to overlapping clinical features with benign prostatic hyperplasia (BPH) and limitations of existing diagnostic tools like PSA tests, which yield high false-positive rates. This study investigat...
BACKGROUND: Lymphoma is a severe condition with high mortality rates, often requiring ICU admission. Traditional risk stratification tools like SOFA and APACHE scores struggle to capture complex clinical interactions. Machine learning (ML) models off...
OBJECTIVE: Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. This study aims to explore the correlation between the spatial distribution of lymphocyte aggregates and the prognosis of MIBC using deep learning.
Neurology(R) neuroimmunology & neuroinflammation
Aug 19, 2025
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)...
Cancer imaging : the official publication of the International Cancer Imaging Society
Aug 19, 2025
BACKGROUND: According to PI-RADS v2.1, peripheral PI-RADS 3 lesions are upgraded to PI-RADS 4 if dynamic contrast-enhanced MRI is positive (3+1 lesions), however those lesions are radiologically challenging. We aimed to define criteria by expert cons...
BACKGROUND: Older patients with ischemic stroke often have a large number of medical needs, technophobia refers to the irrational anxiety and fear of digital technologies such as mobile communication equipment, artificial intelligence and robots, res...
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