AIMC Topic: Animals

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Explicit error coding can mediate gain recalibration in continuous bump attractor networks.

Nature communications
Continuous bump attractor networks (CBANs) are a prevailing model for how neural circuits represent continuous variables. CBANs maintain these representations by temporally integrating inputs that encode differential (i.e., incremental) changes to a ...

Remote automated delivery of mechanical stimuli coupled to brain recordings in behaving mice.

eLife
The canonical framework for testing pain and mechanical sensitivity in rodents is manual delivery of stimuli to the paw. However, this approach is time-consuming, produces variability in results, requires significant training, and is ergonomically un...

E-Sort: empowering end-to-end neural network for multi-channel spike sorting with transfer learning and fast post-processing.

Journal of neural engineering
Spike sorting, which involves detecting and attributing spikes to their putative neurons from extracellular recordings, is a common process in electrophysiology and brain-computer interface systems. Recent advances in large-scale neural recording tec...

New bridging eco-acoustic indices inspired by deep neural networks for fine-grained bird vocalization recognition across diurnal cycles.

PloS one
Revealing difference in bird vocalization changes from the perspectives of song recognition and acoustic indices has become a hot topic and challenge in recent ecological landscape research. This paper proposes a fine-grained (Dawn, noon, night) bird...

High throughput machine learning pipeline to characterize larval zebrafish motor behavior.

PloS one
Using machine learning, we developed models that rigorously detect and classify larval zebrafish spontaneous and stimulus-evoked behaviors in various well plate formats. Zebrafish are an ideal model system for investigating the neural substrates unde...

4-Hydroxy-2,5-dihydrothiazole derivatives as a new class of small-molecule antibiotics for MRSA: AI-integrated design, chemical synthesis and biological evaluation.

European journal of medicinal chemistry
Staphylococcus aureus (S. aureus) is one of the most concerned Gram-positive bacteria due to its resistance to the commonly used antibiotics, methicillin. To address the threat of methicillin-resistant S. aureus (MRSA), new classes of antibiotics are...

Integrated machine learning identifies biomarkers for bilirubin-induced Alzheimer's disease-like lesions in neonates and adults.

Scientific reports
Neurological impairments resulting from bilirubin encephalopathy represent a hallmark of bilirubin's neurotoxic effects. Earlier research suggests that bilirubin may contribute to Alzheimer's disease (AD) pathology by inducing neuronal necrosis and a...

Investigating environmental determinants and spatiotemporal dynamics of highly pathogenic avian influenza H5N1 outbreaks in India through machine learning.

Scientific reports
Avian Influenza (AI), caused by highly pathogenic strains of influenza viruses, poses a significant threat to poultry populations and public health worldwide. This study offers a comprehensive evaluation of the spatial and temporal dynamics of HPAI o...

Single-cell multi-omics uncovers CPS1 as a breast cancer immune evasion therapeutic target.

Scientific reports
Despite significant advances in early detection and therapeutic interventions, breast cancer persists as the most frequently diagnosed malignancy and the leading cause of cancer-related deaths among women globally. Although multiple prognostic signat...

Research on egg yolk color detection based on near infrared spectroscopy and machine vision.

Analytical methods : advancing methods and applications
Yolk color is a key indicator of egg quality, as customers prefer eggs with intensely yellow yolks, which also signal nutrient richness. At present, the commonly used method for yolk color detection is to open the eggs and evaluate the yolk color usi...