AIMC Topic: Animals

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Microrobots for Antibiotic-Resistant Skin Colony Eradication.

ACS applied materials & interfaces
Self-propelled nano- and micromachines have immense potential as autonomous seek-and-act devices in biomedical applications. In this study, we present microrobots constructed with inherently biocompatible materials and propulsion systems tailored to ...

Photocatalytic microrobots for treating bacterial infections deep within sinuses.

Science robotics
Microrobotic techniques are promising for treating biofilm infections located deep within the human body. However, the presence of highly viscous pus presents a formidable biological barrier, severely restricting targeted and minimally invasive treat...

Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments.

eNeuro
Marker-based motion capture (MBMC) is a powerful tool for precise, high-speed, three-dimensional tracking of animal movements, enabling detailed study of behaviors ranging from subtle limb trajectories to broad spatial exploration. Despite its proven...

CATransU-Net: Cross-attention TransU-Net for field rice pest detection.

PloS one
Accurate detection of rice pests in field is a key problem in field pest control. U-Net can effectively extract local image features, and Transformer is good at dealing with long-distance dependencies. A Cross-Attention TransU-Net (CATransU-Net) mode...

CellSeg3D, Self-supervised 3D cell segmentation for fluorescence microscopy.

eLife
Understanding the complex three-dimensional structure of cells is crucial across many disciplines in biology and especially in neuroscience. Here, we introduce a set of models including a 3D transformer (SwinUNetR) and a novel 3D self-supervised lear...

Establishing identifiable characteristic fingerprints of mulberry leaves: Integrating chemical composition and bioactivity through machine learning.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: Mulberry leaves (Morus alba L.) are used in traditional Chinese medicine to clear the lungs and dispel wind-heat. Despite their common use, chemical reference substance rely solely on rutin, which may not reflect their...

Cold receptor TRPM8 as a target for migraine-associated pain and affective comorbidities.

The journal of headache and pain
BACKGROUND: Genetic variations in the Trpm8 gene that encodes the cold receptor TRPM8 have been linked to protection against polygenic migraine, a disabling condition primarily affecting women. Noteworthy, TRPM8 has been recently found in brain areas...

Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury.

Signal transduction and targeted therapy
Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and chronic traumatic encephalopathy, yet the underlying molec...

Use of Artificial Neural Networks (ANNs) to assess xenobiotics in a river catchment using macroinvertebrates as bioindicators.

Aquatic toxicology (Amsterdam, Netherlands)
The Danube flows through various European regions, exposing its aquatic ecosystem to multiple stressors, including dams, canalization, and agricultural activities. Fertilizers, manures, pesticides, animal husbandry activities, irrigation practices, d...

Triclosan exposure potentiates ischemic stroke risk: Multi-omics integration and molecular docking unveil neurotoxic mechanisms.

Ecotoxicology and environmental safety
This study applied network toxicology and multimodal biological approaches integrated with machine learning to systematically identify four TCS-IS-related genes, providing a comprehensive understanding of the pathophysiological relationship between t...