AIMC Topic: Animals
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Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.
Frontiers in immunology
May 29, 2025
BACKGROUND: Traditional Chinese medicine and food deer antler has been extensively used in bone regeneration, but its molecular mechanisms remain poorly understood. Preliminary investigations suggest deer antler contains bioactive compounds that infl...
Eyes Are the Windows to the Soul: Reviewing the Possible Use of the Retina to Indicate Traumatic Brain Injury.
International journal of molecular sciences
May 28, 2025
Traumatic brain injury (TBI) induces complex molecular and cellular responses, often leading to vision deterioration and potential mortality. Current objective diagnostic methods are limited, necessitating the development of novel tools to assess dis...
The impact of aging on achilles tendon ossification in mice.
BMC musculoskeletal disorders
May 28, 2025
BACKGROUND: Heterotopic ossification is a frequent complication of soft tissue injuries, particularly in tendons. Although ossification in tendon tissue has been reported in a range of aging and disease models, the underlying biomarkers and mechanism...
Gasdermin D drives the systemic storm and mortality after trauma with hemorrhage to a greater degree in biological females than males.
Science translational medicine
May 28, 2025
Severe injury accompanied by hemorrhagic shock triggers an early release of cell constituents into the circulation, referred to as the systemic storm. The systemic storm drives the systemic inflammatory response and is associated with increased morta...
An automatic approach for the classification of lumpy skin disease in cattle.
Tropical animal health and production
May 28, 2025
Lumpy Skin Disease (LSD) presents significant risks and economic challenges to global cattle farming. Effective and accurate classification of LSD is essential for managing the disease and reducing its impacts. Manual diagnosis is time-consuming, lab...
Breaking the cycle of parasitic diseases with edutainment: The intersection of entertainment and education.
PLoS neglected tropical diseases
May 28, 2025
Parasitic diseases represent a substantial public health challenge worldwide. Traditional educational strategies have often fallen short in driving sustained behavioral shifts that are nonetheless essential for reducing the burden of these diseases. ...
Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq.
Frontiers in immunology
May 28, 2025
BACKGROUND: Mitophagy is a highly conserved cellular process in eukaryotic cells that selectively clears dysfunctional or damaged mitochondria through autophagy mechanisms to maintain mitochondrial homeostasis. However, the role of mitophagy in the p...
Easy and Fast Discrimination of Female Sand Flies from Species with Infrared Spectroscopy and Multivariate Analysis.
Analytical chemistry
May 26, 2025
Accurate identification of sandfly species is critical for controlling and preventing the spread of visceral leishmaniasis, a major public health concern in Latin America. Morphological similarities between female and present a significant challeng...
Advances in brain-targeted delivery strategies and natural product-mediated enhancement of blood-brain barrier permeability.
Journal of nanobiotechnology
May 26, 2025
The blood-brain barrier (BBB) represents a formidable challenge in the treatment of neurological disorders, as it restricts the passage of most therapeutic agents into the central nervous system (CNS). Research in brain-targeted delivery strategies a...
Volumetric atlas of the rat inner ear from microCT and iDISCO+ cleared temporal bones.
PeerJ
May 26, 2025
BACKGROUND: Volumetric atlases are an invaluable tool in neuroscience and otolaryngology, greatly aiding experiment planning and surgical interventions, as well as the interpretation of experimental and clinical data. The rat is a major animal model ...
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