AIMC Topic: Antineoplastic Agents, Phytogenic
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Machine Learning Methods to Extract Documentation of Breast Cancer Symptoms From Electronic Health Records.
Journal of pain and symptom management
Feb 27, 2018
CONTEXT: Clinicians document cancer patients' symptoms in free-text format within electronic health record visit notes. Although symptoms are critically important to quality of life and often herald clinical status changes, computational methods to a...
Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dec 26, 2017
Chemical composition and antioxidative, genotoxic and cytotoxic potential of essential oil (EO) and post-distillation waste (PDW) of Serbian Juniperus communis L. var. saxatilis Pall. was studied in human lung carcinoma (A549) and normal lung fibrobl...
Juniperus
Doxorubicin
Mutagens
Cell Division
Rats
G2 Phase
Apoptosis
Cell Line
Antineoplastic Agents, Phytogenic
Chromatography, Liquid
Drug Screening Assays, Antitumor
Tandem Mass Spectrometry
Gas Chromatography-Mass Spectrometry
Male
Cell Line, Tumor
Antioxidants
Plant Extracts
Humans
Female
Animals
Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel.
Phytochemical analysis : PCA
Dec 20, 2017
INTRODUCTION: Paclitaxel (Tax) is a diterpene alkaloid isolated from Taxus species and has proved clinically effective in treating a number of malignancies. Current quantitative analytical methods for Tax such as high-performance liquid chromatograph...
Label-free detection of cellular drug responses by high-throughput bright-field imaging and machine learning.
Scientific reports
Sep 29, 2017
In the last decade, high-content screening based on multivariate single-cell imaging has been proven effective in drug discovery to evaluate drug-induced phenotypic variations. Unfortunately, this method inherently requires fluorescent labeling which...
Anticancer and anti-inflammatory activities of girinimbine isolated from .
Drug design, development and therapy
Dec 28, 2016
Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a...
Apoptosis
Lipopolysaccharides
Dose-Response Relationship, Drug
Cell Survival
Animals
Mice
Nitric Oxide
Cell Proliferation
Zebrafish
Alkaloids
HT29 Cells
Tumor Cells, Cultured
Antineoplastic Agents, Phytogenic
Drug Screening Assays, Antitumor
Structure-Activity Relationship
Anti-Inflammatory Agents, Non-Steroidal
Humans
Cytokines
Murraya
Kinetics Extraction Modelling and Antiproliferative Activity of Water Extract.
TheScientificWorldJournal
Dec 26, 2016
is widely grown in tropical Asia and locally known "belalai gajah" or Sabah snake grass. It has been used as a natural product to treat skin rashes, snake bites, lesion caused by herpes, diabetes, fever, and cancer. Therefore, the objectives of this...
COF-1-modified magnetic nanoparticles for highly selective and efficient solid-phase microextraction of paclitaxel.
Talanta
Dec 21, 2016
Novel covalent organic framework-1 modified magnetic nanoparticles (M-COF-1) were prepared for extraction of paclitaxel from rat plasma samples. Paclitaxel is an important anti-cancer drug in clinical chemotherapy. COF-1 was immobilized on the surfac...
Pectic Oligosaccharide from tomato exhibiting anticancer potential on a gastric cancer cell line: Structure-function relationship.
Carbohydrate polymers
Dec 20, 2016
Pectic Polysaccharide (PP) from dietary sources has been known to prevent cancer growth and hence impede cancer progression. We evaluated anticancer effect of Pectic-Oligosaccharide isolated from Sour Raw Tomato (SrTPO); its bioavailability and struc...
PHENOLIC PROFILE OF L. GROWING IN EGYPT AND ITS CYTOTOXIC AND ANTIVIRAL ACTIVITIES.
African journal of traditional, complementary, and alternative medicines : AJTCAM
Sep 29, 2016
BACKGROUND: L (Asteraceae), is one of the most attractive plants growing wildly in Sinai, and is not well investigated for its phytochemical constituents. This study represents the first in-depth characterization of the phenolic profile of the aeria...
O-naphthoquinone isolated from Capraria biflora L. induces selective cytotoxicity in tumor cell lines.
Genetics and molecular research : GMR
Dec 21, 2015
Biflorin is an o-naphthoquinone isolated from the roots of the plant Capraria biflora L. (Scrophulariaceae). In this study, the cytotoxic effects of biflorin were verified, and late apoptosis was detected in various cancer cell lines by in situ analy...
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