Renal stones (RS) are common urologic condition with unclear pathogenesis. Role of aging-related differentially expressed genes (ARDEGs) in RS remains poorly understood. This study aims to identify potential aging-related biomarkers for RS, explore t...
Biomarkers are crucial in aiding in disease diagnosis, prognosis, and treatment selection. Machine learning (ML) has emerged as an effective tool for identifying novel biomarkers and enhancing predictive modelling. However, sex-based bias in ML algor...
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...
Blood-based biomarkers in epilepsy could constitute important research tools advancing neurobiological understanding and valuable clinical tools for better diagnosis and follow-up. An interesting question is whether biomarker patterns could contribut...
Neurology(R) neuroimmunology & neuroinflammation
Jun 30, 2025
BACKGROUND AND OBJECTIVES: Emerging evidence suggests that oral health conditions may exacerbate migraine, and saliva is a potential source of biomarkers for migraine. The 3-way interaction of the oral-gut-brain axis has been implicated in several ne...
Inflammatory bowel disease (IBD) often lacks a definitive diagnostic standard, leading to diagnoses through exclusion. This study aimed to create a predictive model for IBD using bioinformatics and deep learning while identifying potential biomarkers...
The journal of prevention of Alzheimer's disease
Jun 28, 2025
BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, and early diagnosis is crucial to enable effective interventions. Currently, Alzheimer's disease is diagnosed through cognitive assessments, brain imaging and fluid biomarkers ...
INTRODUCTION: Enhancing paediatric asthma diagnosis is crucial. Molecular analysis of exhaled breath is a rapidly evolving field aimed at harnessing established and innovative technologies for clinical applications. This study evaluates the feasibili...
BACKGROUND: Substance use disorder (SUD) involves excessive substance consumption and persistent reward-seeking behaviors, leading to serious physical, cognitive, and social consequences. This disorder is a global health crisis tied to increased mort...
γ neuromodulation has emerged as a promising strategy for addressing neurological and psychiatric disorders, particularly in regulating executive and cognitive functions. This review explores the latest neuromodulation techniques, focusing on the cri...
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