AIMC Topic: Biopsy

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A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.

Hepatology (Baltimore, Md.) Jun 24, 2021
BACKGROUND AND AIMS: Manual histological assessment is currently the accepted standard for diagnosing and monitoring disease progression in NASH, but is limited by variability in interpretation and insensitivity to change. Thus, there is a critical n...
Humans Liver Cirrhosis Liver Randomized Controlled Trials as Topic Biopsy Non-alcoholic Fatty Liver Disease Reproducibility of Results Severity of Illness Index Deep Learning Image Processing, Computer-Assisted
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Deep learning-based framework for the distinction of membranous nephropathy: a new approach through hyperspectral imagery.

BMC nephrology Jun 19, 2021
BACKGROUND: Common subtypes seen in Chinese patients with membranous nephropathy (MN) include idiopathic membranous nephropathy (IMN) and hepatitis B virus-related membranous nephropathy (HBV-MN). However, the morphologic differences are not visible ...
Biopsy Feasibility Studies Glomerulonephritis, Membranous Artifacts Humans Male Diagnosis, Computer-Assisted Female Deep Learning Adult Diagnosis, Differential
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Clinical characteristics and oncological outcomes in negative multiparametric MRI patients undergoing robot-assisted radical prostatectomy.

The Prostate May 31, 2021
BACKGROUND: Efforts are ongoing to try and find ways to reduce the number of unnecessary prostate biopsies without missing clinically significant prostate cancers (csPCa). The utility of multiparametric magnetic resonance imaging (mpMRI) in detecting...
Neoplasm Grading Treatment Outcome Humans Prostatectomy Robotics Retrospective Studies Margins of Excision Biopsy Prostatic Neoplasms Male Multiparametric Magnetic Resonance Imaging False Negative Reactions Prostate-Specific Antigen Middle Aged Black or African American
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Deep-Learning-Driven Quantification of Interstitial Fibrosis in Digitized Kidney Biopsies.

The American journal of pathology May 23, 2021
Interstitial fibrosis and tubular atrophy (IFTA) on a renal biopsy are strong indicators of disease chronicity and prognosis. Techniques that are typically used for IFTA grading remain manual, leading to variability among pathologists. Accurate IFTA ...
Adult Male Middle Aged Humans Infant Biopsy Female Deep Learning Fibrosis Adolescent Infant, Newborn Image Interpretation, Computer-Assisted Child, Preschool Aged Child Aged, 80 and over Kidney Diseases Young Adult
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Artificial intelligence for advance requesting of immunohistochemistry in diagnostically uncertain prostate biopsies.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc May 20, 2021
The use of immunohistochemistry in the reporting of prostate biopsies is an important adjunct when the diagnosis is not definite on haematoxylin and eosin (H&E) morphology alone. The process is however inherently inefficient with delays while waiting...
Workflow Image Interpretation, Computer-Assisted Immunohistochemistry Pathology, Clinical Male Deep Learning Prostatic Neoplasms Biopsy Humans Automation, Laboratory
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Quantitative assessment of inflammatory infiltrates in kidney transplant biopsies using multiplex tyramide signal amplification and deep learning.

Laboratory investigation; a journal of technical methods and pathology May 18, 2021
Delayed graft function (DGF) is a strong risk factor for development of interstitial fibrosis and tubular atrophy (IFTA) in kidney transplants. Quantitative assessment of inflammatory infiltrates in kidney biopsies of DGF patients can reveal predicti...
Humans Kidney Transplantation Female Aged Adult Male Middle Aged Deep Learning Kidney Transplantation Immunology Inflammation Renal Insufficiency, Chronic Biopsy Immunohistochemistry
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Artificial intelligence could alert for focal skeleton/bone marrow uptake in Hodgkin's lymphoma patients staged with FDG-PET/CT.

Scientific reports May 17, 2021
To develop an artificial intelligence (AI)-based method for the detection of focal skeleton/bone marrow uptake (BMU) in patients with Hodgkin's lymphoma (HL) undergoing staging with FDG-PET/CT. The results of the AI in a separate test group were comp...
Musculoskeletal System Radiopharmaceuticals Fluorodeoxyglucose F18 Hodgkin Disease Skeleton Positron Emission Tomography Computed Tomography Biopsy Bone Marrow Aged Biological Transport Aged, 80 and over Young Adult Humans Adult Neural Networks, Computer Male Artificial Intelligence Female Middle Aged Adolescent Child Multimodal Imaging
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Development and head-to-head comparison of machine-learning models to identify patients requiring prostate biopsy.

BMC urology May 16, 2021
BACKGROUND: Machine learning has many attractive theoretic properties, specifically, the ability to handle non predefined relations. Additionally, studies have validated the clinical utility of mpMRI for the detection and localization of CSPCa (Gleas...
Biopsy Patient Selection Multiparametric Magnetic Resonance Imaging Humans Machine Learning Retrospective Studies Aged Male Middle Aged Models, Theoretical Prostate
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Validation of a machine learning approach using FIB-4 and APRI scores assessed by the metavir scoring system: A cohort study.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology May 10, 2021
BACKGROUND AND STUDY AIM: The study aim was to improve and validate the accuracy of the fibrosis-4 (FIB-4) and aspartate aminotransferase-to-platelet ratio index (APRI) scores for use in a potential machine-learning (ML) method that accurately predic...
Machine Learning Biomarkers Retrospective Studies Adult Cohort Studies Humans Liver Cirrhosis Biopsy Fibrosis Aspartate Aminotransferases
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Texture analysis of muscle MRI: machine learning-based classifications in idiopathic inflammatory myopathies.

Scientific reports May 10, 2021
To develop a machine learning (ML) model that predicts disease groups or autoantibodies in patients with idiopathic inflammatory myopathies (IIMs) using muscle MRI radiomics features. Twenty-two patients with dermatomyositis (DM), 14 with amyopathic ...
Humans Machine Learning Retrospective Studies Female Reproducibility of Results Image Interpretation, Computer-Assisted Muscles ROC Curve Polymyositis Aged Magnetic Resonance Imaging Urokinase-Type Plasminogen Activator Adult Diagnosis, Differential Antibodies, Antinuclear Male Biopsy Antigens, Ly Middle Aged Dermatomyositis
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