AIMC Topic: Brain

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Neural models for detection and classification of brain states and transitions.

Communications biology
Exploring natural or pharmacologically induced brain dynamics, such as sleep, wakefulness, or anesthesia, provides rich functional models for studying brain states. These models allow detailed examination of unique spatiotemporal neural activity patt...

An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology.

Neuron
Neurotechnologies and genetic tools for dissecting neural circuit functions have advanced rapidly over the past decade although the development of complementary pharmacological methodologies has comparatively lagged. Understanding the precise pharmac...

CLIC1 and IFITM2 expression in brain tissue correlates with cognitive impairment via immune dysregulation in sepsis and Alzheimer's disease.

International immunopharmacology
BACKGROUND: Sepsis, a life-threatening condition driven by dysregulated host responses to infection, is associated with long-term cognitive impairments resembling Alzheimer's disease (AD). However, the molecular mechanisms linking sepsis-induced cogn...

FetDTIAlign: A deep learning framework for affine and deformable registration of fetal brain dMRI.

NeuroImage
Diffusion MRI (dMRI) offers unique insights into the microstructure of fetal brain tissue in utero. Longitudinal and cross-sectional studies of fetal dMRI have the potential to reveal subtle but crucial changes associated with normal and abnormal neu...

Enhancing neurological disease diagnostics: fusion of deep transfer learning with optimization algorithm for acute brain stroke prediction using facial images.

Scientific reports
Stroke is a main risk to life and fitness in current society, particularly in the aging population. Also, the stroke is recognized as a cerebrovascular accident. It contains a nervous illness, which can result from haemorrhage or ischemia of the brai...

Integrated brain connectivity analysis with fMRI, DTI, and sMRI powered by interpretable graph neural networks.

Medical image analysis
Multimodal neuroimaging data modeling has become a widely used approach but confronts considerable challenges due to their heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability necessitate...

Alterations in static and dynamic functional network connectivity in chronic low back pain: a resting-state network functional connectivity and machine learning study.

Neuroreport
Low back pain (LBP) is a prevalent pain condition whose persistence can lead to changes in the brain regions responsible for sensory, cognitive, attentional, and emotional processing. Previous neuroimaging studies have identified various structural a...

Natural language processing models reveal neural dynamics of human conversation.

Nature communications
Through conversation, humans engage in a complex process of alternating speech production and comprehension to communicate. The neural mechanisms that underlie these complementary processes through which information is precisely conveyed by language,...

Ensemble deep learning for Alzheimer's disease diagnosis using MRI: Integrating features from VGG16, MobileNet, and InceptionResNetV2 models.

PloS one
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain, leading to distinctive patterns of neuronal dysfunction and the cognitive decline emblematic of de...

Structural brain pattern abnormalities in tinnitus with and without hearing loss.

Hearing research
OBJECTIVE: Subjective tinnitus often coexists with hearing loss, and they share common pathophysiological mechanisms. This comorbidity induces whole-brain gray matter volume (GMV) alterations, manifesting as distributed structural changes in neural n...