AIMC Topic: Case-Control Studies

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Machine learning algorithm-based risk prediction model of coronary artery disease.

Molecular biology reports
In view of high mortality associated with coronary artery disease (CAD), development of an early predicting tool will be beneficial in reducing the burden of the disease. The database comprising demographic, conventional, folate/xenobiotic genetic ri...

Using a deep learning network to recognise low back pain in static standing.

Ergonomics
Low back pain (LBP) remains one of the most prevalent musculoskeletal disorders, while algorithms that able to recognise LBP patients from healthy population using balance performance data are rarely seen. In this study, human balance and body sway p...

Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy.

BMC bioinformatics
BACKGROUND: Spastic cerebral palsy (CP) is a leading cause of physical disability. Most people with spastic CP are born with it, but early diagnosis is challenging, and no current biomarker platform readily identifies affected individuals. The aim of...

A study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set.

Journal of biomedical informatics
Recently, recurrent neural networks (RNNs) have been applied in predicting disease onset risks with Electronic Health Record (EHR) data. While these models demonstrated promising results on relatively small data sets, the generalizability and transfe...

The comparison of pleural fluid TNF-α levels in tuberculous and nontuberculous pleural effusion.

The Indian journal of tuberculosis
BACKGROUND: Tuberculous pleural effusion is the manifestation of Mycobacterium tuberculosis infection in pleura. With existing means, it is difficult to establish the diagnosis of tuberculosis (TB) and non-TB pleural effusions; thus, establishing the...

A metabolomics-based approach for non-invasive screening of fetal central nervous system anomalies.

Metabolomics : Official journal of the Metabolomic Society
BACKGROUND: Central nervous system anomalies represent a wide range of congenital birth defects, with an incidence of approximately 1% of all births. They are currently diagnosed using ultrasound evaluation. However, there is strong need for a more a...

Effect of Health and Training on Ultrasensitive Cardiac Troponin in Marathon Runners.

The journal of applied laboratory medicine
PURPOSE: Cardiac troponin (cTn) is the gold standard biomarker for assessing cardiac damage. Previous studies have demonstrated increases in plasma cTn because of extreme exercise, including marathon running. We developed an easy-to-use, ultrasensiti...

Automatic Cone Photoreceptor Localisation in Healthy and Stargardt Afflicted Retinas Using Deep Learning.

Scientific reports
We present a robust deep learning framework for the automatic localisation of cone photoreceptor cells in Adaptive Optics Scanning Light Ophthalmoscope (AOSLO) split-detection images. Monitoring cone photoreceptors with AOSLO imaging grants an excell...

A web-based system for neural network based classification in temporomandibular joint osteoarthritis.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
OBJECTIVE: The purpose of this study is to describe the methodological innovations of a web-based system for storage, integration and computation of biomedical data, using a training imaging dataset to remotely compute a deep neural network classifie...