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Colorectal Neoplasms

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C2P-GCN: Cell-to-Patch Graph Convolutional Network for Colorectal Cancer Grading.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Graph-based learning approaches, due to their ability to encode tissue/organ structure information, are increasingly favored for grading colorectal cancer histology images. Recent graph-based techniques involve dividing whole slide images (WSIs) into...

Towards the development of a FAIR-compliant biomedical ontology for colorectal cancer.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Despite the widespread development of ontologies in many domains of healthcare, the field of colorectal cancer (CRC) presents a notable gap considering the lack of standardized data models tailored to the CRC domain. To address this gap, we developed...

Cost-Effectiveness for Artificial Intelligence in Colonoscopy.

Gastrointestinal endoscopy clinics of North America
Artificial intelligence (AI) is set to transform the field of colonoscopy through the implementation of computer-assisted detection and diagnosis. While over 20 randomized controlled trials have demonstrated the efficacy of AI in increasing adenoma d...

Constructing a Prognostic Model for Subtypes of Colorectal Cancer Based on Machine Learning and Immune Infiltration-Related Genes.

Journal of cellular and molecular medicine
This study constructed a prognostic model combining machine learning-based immune infiltration-related genes in each CRC subtype. We used publicly accessible gene expression data and clinical information on colorectal cancer patients. Integrated bioi...

Machine Learning-Enabled Non-Invasive Screening of Tumor-Associated Circulating Transcripts for Early Detection of Colorectal Cancer.

International journal of molecular sciences
Colorectal cancer (CRC) is a major cause of cancer-related mortality, highlighting the need for accurate and non-invasive diagnostics. This study assessed the utility of tumor-associated circulating transcripts (TACTs) as biomarkers for CRC detection...

Identification of a gene signature and prediction of overall survival of patients with stage IV colorectal cancer using a novel machine learning approach.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
OBJECTIVE: We sought to characterize unique gene signature patterns associated with worse overall survival (OS) among patients with stage IV colorectal cancer (CRC) using a machine learning (ML) approach.

Artificial intelligence assessment of tissue-dissection efficiency in laparoscopic colorectal surgery.

Langenbeck's archives of surgery
PURPOSE: Several surgical-skill assessment tools emphasize the importance of efficient tissue-dissection, whose assessment relies on human judgment and is thus subject to bias. Automated assessment may help solve this problem. This study aimed to ver...

Leveraging Radiomics and Hybrid Quantum-Classical Convolutional Networks for Non-Invasive Detection of Microsatellite Instability in Colorectal Cancer.

Molecular imaging and biology
PURPOSE: The goal of this study is to create a novel framework for identifying MSI status in colorectal cancer using advanced radiomics and deep learning strategies, aiming to enhance clinical decision-making and improve patient outcomes in oncology.

A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.

Nature biomedical engineering
The quantification of circulating tumour DNA (ctDNA) in blood enables non-invasive surveillance of cancer progression. Here we show that a deep-learning model can accurately quantify ctDNA from the density distribution of cell-free DNA-fragment lengt...

Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer.

ACS nano
Colorectal cancer (CRC) remains a formidable threat to human health, with considerable challenges persisting in its diagnosis, particularly during the early stages of the malignancy. In this study, we elucidated that fecal extracellular vesicle micro...