Pathology diagnosis of colorectal cancer is time-consuming and requires a high level of expertise. However, it is an essential step towards establishing the adequate treatment. The need to analyse a large number of these histopathological images call...
International journal of colorectal disease
Oct 21, 2025
BACKGROUND: The emergence of artificial intelligence (AI) has greatly promoted the development of the field of medical image analysis, but the potential benefits of AI-assisted colonoscopy and diagnosis (CADe/CADx) for the detection rate of colorecta...
European journal of cancer (Oxford, England : 1990)
Oct 20, 2025
STUDY AIM: Early detection of distant metastases is crucial, but current imaging detects them only when radiographically visible. This study reported subvisual chest CT signals could serve as early biomarkers for impending lung metastasis before radi...
BACKGROUND: Microsatellite stability (MSS) colorectal cancers (CRCs) have a limited response to immune checkpoint inhibitors (ICIs) compared to microsatellite instability-high (MSI-H) CRCs. Nevertheless, previous studies have shown that some MSS CRCs...
The Journal of clinical investigation
Oct 15, 2025
Hypoxia in the tumor microenvironment promotes lymphatic metastasis, yet the role of cancer-associated fibroblasts (CAFs) in this process remains insufficiently elucidated in colorectal cancer (CRC). In this study, we developed a large language model...
Medical science monitor : international medical journal of experimental and clinical research
Oct 10, 2025
BACKGROUND Perineural invasion (PNI) is strongly associated with poor clinical outcomes in colorectal cancer (CRC). However, no machine learning diagnostic model based on pathomics has been established for PNI detection in CRC. To address this issue,...
Colorectal cancer (CRC) poses a significant global health burden, where early and accurate diagnosis is vital to improving patient outcomes. However, the structural complexity of CRC histopathological images renders manual analysis time-consuming and...
Accurate polyp detection is essential for the early diagnosis and effective treatment of colorectal cancer (CRC). However, colonoscopy videos in real-world clinical settings present significant challenges, often causing existing algorithms to fail. C...
Colorectal cancer (CRC) remains a major global health burden, necessitating more effective and selective therapeutic approaches. Nanocarrier-based drug delivery systems offer significant advantages by enhancing drug accumulation in tumors, reducing o...
BACKGROUND: Patients with colorectal cancer (CRC) often experience chemotoxicity that impacts treatment adherence, survival, and quality of life. Early screening for chemotoxicity risk is vital, yet comprehensive predictive models are lacking. The ob...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.