AIMC Topic: Disease-Free Survival

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Predicting Clinical Outcomes in Colorectal Cancer Using Machine Learning.

Studies in health technology and informatics Jan 1, 2018
Using gene markers and other patient features to predict clinical outcomes plays a vital role in enhancing clinical decision making and improving prognostic accuracy. This work uses a large set of colorectal cancer patient data to train predictive mo...
Neural Networks, Computer Machine Learning Prognosis Colorectal Neoplasms Disease-Free Survival Humans
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Unsupervised consensus cluster analysis of [18F]-fluoroethyl-L-tyrosine positron emission tomography identified textural features for the diagnosis of pseudoprogression in high-grade glioma.

Oncotarget Jan 31, 2017
RATIONALE: Timely detection of pseudoprogression (PSP) is crucial for the management of patients with high-grade glioma (HGG) but remains difficult. Textural features of O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography (FET-PET) mirror ...
Retrospective Studies Unsupervised Machine Learning Female Predictive Value of Tests Reproducibility of Results Positron Emission Tomography Computed Tomography Time Factors Aged Neoplasm Grading Treatment Outcome Radiopharmaceuticals Adult Radiographic Image Interpretation, Computer-Assisted Glioma Disease-Free Survival Humans Magnetic Resonance Imaging Brain Neoplasms Kaplan-Meier Estimate Cluster Analysis Male Tyrosine Middle Aged Disease Progression Pilot Projects
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A comparative phase III clinical study to evaluate efficacy and safety of TrastuRel™ (biosimilar trastuzumab) and innovator trastuzumab in patients with metastatic human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer.

Indian journal of cancer Jan 1, 2017
INTRODUCTION: The present study for biosimilar trastuzumab was a multicentric, randomized, two-arm parallel-group, comparative phase III study in patients with metastatic breast cancer.
Biosimilar Pharmaceuticals Humans Breast Neoplasms Trastuzumab Drug-Related Side Effects and Adverse Reactions Middle Aged Paclitaxel Female India Disease-Free Survival Aged Antineoplastic Combined Chemotherapy Protocols Receptor, ErbB-2 Adult Remission Induction
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Radical gastrectomy for gastric cancer at Tata Memorial Hospital.

Indian journal of cancer Jan 1, 2017
AIM: Tata Memorial Hospital is one of the high-volume tertiary care referral centers for gastric cancer (GC) in India. We aimed to analyze the outcomes after surgery for GC.
Humans Female Aged Disease-Free Survival Stomach Neoplasms Adult Postoperative Period Male Length of Stay Middle Aged India Hospitals Lymph Nodes Lymph Node Excision Gastrectomy
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A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery.

Oncotarget Apr 19, 2016
Nearly 20% patients with stage II A colon cancer will develop recurrent disease post-operatively. The present study aims to develop a scoring system based on Artificial Neural Network (ANN) model for predicting 10-year survival outcome. The clinical ...
Female Risk Factors Aged Adult Biomarkers, Tumor Humans Neural Networks, Computer Neoplasm Recurrence, Local Colonic Neoplasms Disease-Free Survival Kaplan-Meier Estimate Male Middle Aged ROC Curve Area Under Curve
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A chemotherapy response classifier based on support vector machines for high-grade serous ovarian carcinoma.

Oncotarget Jan 19, 2016
Long-term outcome of high-grade serous epithelial ovarian carcinoma (HGSOC) remains poor as a result of recurrence and the emergence of drug resistance. Almost all the patients were given the same platinum-based chemotherapy after debulking surgery e...
Support Vector Machine Ovarian Neoplasms Neoplasm Recurrence, Local Disease-Free Survival Carcinoma, Ovarian Epithelial Female Middle Aged Antineoplastic Agents Cohort Studies Drug Resistance, Neoplasm Neoplasms, Glandular and Epithelial Response Evaluation Criteria in Solid Tumors Humans Decision Support Techniques
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An audit of cytoreductive surgeries in ovarian cancer from a rural based cancer center.

Indian journal of cancer Jan 1, 2016
BACKGROUND AND OBJECTIVE: Ovarian cancers are frequently seen at an advanced stage in our center. This audit was planned to see the morbidity and efficacy of different types of cytoreductive surgeries (radical vs. ultra-radical) done in such patients...
Adult Cytoreduction Surgical Procedures Commission on Professional and Hospital Activities Middle Aged Humans Rural Population Retrospective Studies Ovarian Neoplasms Female Disease-Free Survival
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ASSOCIATION BETWEEN MURINE DOUBLE MINUTE 2 - T309G polymorphism and recurrence of hepatocellular carcinoma after surgical treatment.

Arquivos de gastroenterologia Dec 1, 2015
BACKGROUND: Discovery and incorporation of biomarker panels to cancer studies enabled the understanding of genetic variation and its interference in carcinogenesis at molecular level. The potential association between single nucleotide polymorphism (...
Genetic Predisposition to Disease Polymorphism, Single Nucleotide Genotype Treatment Outcome Neoplasm Recurrence, Local Disease-Free Survival Hepatectomy Proto-Oncogene Proteins c-mdm2 Aged, 80 and over Male Humans Middle Aged Liver Neoplasms Carcinoma, Hepatocellular Retrospective Studies Female Risk Factors Aged
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Impact of Positive Surgical Margins after Radical Prostatectomy on Disease Progression and Adjuvant Treatment in Pathologically Localized Prostate Cancer.

Collegium antropologicum Sep 1, 2015
The aim of our study was to evaluate the impact of margin positivity in clinically and pathologically localized prostate cancer (pT2) after radical prostatectomy on biochemical recurrence and time to adjuvant treatment. We analyzed data from 371 pati...
Neoplasm Staging Prostate-Specific Antigen Neoplasm Grading Neoplasm Recurrence, Local Disease-Free Survival Radiotherapy, Adjuvant Chemotherapy, Adjuvant Prostatectomy Neoplasm, Residual Male Humans Middle Aged Aged Disease Progression Time Factors Prostatic Neoplasms
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Aortic Annulus Diameter Affects Durability of the Repaired Bicuspid Aortic Valve.

The Journal of heart valve disease Jul 1, 2015
BACKGROUND AND AIM OF THE STUDY: An investigation was made as to whether the preoperative aortic annular diameter affects the durability of bicuspid aortic valve (BAV) repair in patients who had undergone concomitant root stabilization with subcommis...
Humans Aortic Valve Insufficiency Bicuspid Aortic Valve Disease Heart Valve Diseases Chi-Square Distribution Odds Ratio Middle Aged Retrospective Studies Replantation Time Factors Female Kaplan-Meier Estimate Treatment Outcome Risk Factors Recurrence Aortic Valve Adult Cardiac Valve Annuloplasty Disease-Free Survival Male
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