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Estimation of Machine Learning-Based Models to Predict Dementia Risk in Patients With Atherosclerotic Cardiovascular Diseases: UK Biobank Study.

JMIR aging
BACKGROUND: The atherosclerotic cardiovascular disease (ASCVD) is associated with dementia. However, the risk factors of dementia in patients with ASCVD remain unclear, necessitating the development of accurate prediction models.

Complete Blood Count and Monocyte Distribution Width-Based Machine Learning Algorithms for Sepsis Detection: Multicentric Development and External Validation Study.

Journal of medical Internet research
BACKGROUND: Sepsis is an organ dysfunction caused by a dysregulated host response to infection. Early detection is fundamental to improving the patient outcome. Laboratory medicine can play a crucial role by providing biomarkers whose alteration can ...

Predicting Agitation-Sedation Levels in Intensive Care Unit Patients: Development of an Ensemble Model.

JMIR medical informatics
BACKGROUND: Agitation and sedation management is critical in intensive care as it affects patient safety. Traditional nursing assessments suffer from low frequency and subjectivity. Automating these assessments can boost intensive care unit (ICU) eff...

Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos.

eLife
The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate the adaptive interactions between the oviduct and gamete/embryo, we performed a m...

Development of a tertiary lymphoid structure-based prognostic model for breast cancer: integrating single-cell sequencing and machine learning to enhance patient outcomes.

Frontiers in immunology
BACKGROUND: Breast cancer, a highly prevalent global cancer, poses significant challenges, especially in advanced stages. Prognostic models are crucial to enhance patient outcomes. Tertiary lymphoid structures (TLS) within the tumor microenvironment ...

Deep-learning tool for early identification of non-traumatic intracranial hemorrhage etiology and application in clinical diagnostics based on computed tomography (CT) scans.

PeerJ
BACKGROUND: To develop an artificial intelligence system that can accurately identify acute non-traumatic intracranial hemorrhage (ICH) etiology (aneurysms, hypertensive hemorrhage, arteriovenous malformation (AVM), Moyamoya disease (MMD), cavernous ...

Leveraging diverse cell-death patterns in diagnosis of sepsis by integrating bioinformatics and machine learning.

PeerJ
BACKGROUND: Sepsis is a life-threatening disease causing millions of deaths every year. It has been reported that programmed cell death (PCD) plays a critical role in the development and progression of sepsis, which has the potential to be a diagnosi...

Machine learning-based prediction of distant metastasis risk in invasive ductal carcinoma of the breast.

PloS one
More than 90% of deaths due to breast cancer (BC) are due to metastasis-related complications, with invasive ductal carcinoma (IDC) of the breast being the most common pathologic type of breast cancer and highly susceptible to metastasis to distant o...

Identification and taste presentation characteristics of umami peptides from soybean paste based on peptidomics and virtual screening.

Food chemistry
This research concentrated on soybean paste fermented with Tetragenococcus halophilus, employing peptidomics and machine learning methodologies to screen for novel umami peptides. Taste characteristics of umami peptides were evaluated through sensory...

Non-invasive classification of non-neoplastic and neoplastic gallbladder polyps based on clinical imaging and ultrasound radiomics features: An interpretable machine learning model.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Gallbladder (GB) adenomas, precancerous lesions for gallbladder carcinoma (GBC), lack reliable non-invasive tools for preoperative differentiation of neoplastic polyps from cholesterol polyps. This study aimed to evaluate an interpretable...