AIMC Topic: Female

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Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk.

JCI insight
BACKGROUNDObesity, a growing health concern, often leads to metabolic disturbances, systemic inflammation, and vascular dysfunction. Emerging evidence suggests that adipose tissue-derived extracellular vesicles (adiposomes) may propagate obesity-rela...

Cold receptor TRPM8 as a target for migraine-associated pain and affective comorbidities.

The journal of headache and pain
BACKGROUND: Genetic variations in the Trpm8 gene that encodes the cold receptor TRPM8 have been linked to protection against polygenic migraine, a disabling condition primarily affecting women. Noteworthy, TRPM8 has been recently found in brain areas...

Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.

Physics in medicine and biology
To facilitate implementation of plan-of-the-day (POTD) selection for treating locally advanced cervical cancer (LACC), we developed a POTD assessment tool for CBCT-guided radiotherapy (RT). A female pelvis segmentation model (U-Seg3) is combined with...

Empowering EFL teachers' perceptions of generative AI-mediated self-professionalism.

PloS one
This study intends to empower English as a Foreign Language (EFL) teachers' perceptions of generative artificial intelligence (AI)-mediated self-professionalism in engagement, attitudes, constraints, and solutions. Employing the mixed methods researc...

Intervention through an intelligent technological platform for socio-emotional development and health promotion in adolescents with Type 1 Diabetes Mellitus (emoTICare): A study protocol for randomized controlled trial.

PloS one
BACKGROUND: During adolescence, individuals face various challenges that require adequate psychosocial and emotional adjustment. Additionally, the presence of a chronic illness during this stage, such as Type 1 Diabetes Mellitus (T1DM), introduces ad...

Detection of pre-ictal epileptic events using a self-attention based neural network from raw Neonatal EEG data.

Computers in biology and medicine
Epileptic seizures can occur unpredictably, making real-time monitoring and early warning systems critical, especially in neonatal patients, where timely intervention can significantly improve outcomes. Neonatal seizures are often subtle and difficul...

Covarying gray and white matter networks characterize schizophrenia and bipolar disorders on a continuum: A data fusion machine learning approach and a brain network analysis.

Journal of affective disorders
Schizophrenia (SZ) and Bipolar disorder (BD) share genetic and cerebral abnormalities, supporting an expanded continuum hypothesis. In this paper, we aim to better characterize differences and commonalities of gray and white matter features between S...

A two-stage machine learning-based risk assessment model for intravenous thrombolysis in acute ischemic stroke (AIS): A multi-center modeling study of pooled datasets.

International journal of medical informatics
OBJECTIVE: Develop a two-stage, machine learning-based thrombolysis risk stratification model from existing medical datasets and electronic health records to predict the risk of early hemorrhagic transformation(HT) and in-hospital mortality(IM) follo...

Enhancing rare disease detection with deep phenotyping from EHR narratives: evaluation on Jeune syndrome.

International journal of medical informatics
BACKGROUND: Patients with rare diseases frequently experience misdiagnoses and long diagnostic delays. Accelerating their diagnosis is essential to ensure timely access to appropriate care. Given the increasing availability of EHRs, combining artific...