AIMC Topic: Genotype

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A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support.

Retrovirology
BACKGROUND: CCR5-coreceptor antagonists can be used for treating HIV-2 infected individuals. Before initiating treatment with coreceptor antagonists, viral coreceptor usage should be determined to ensure that the virus can use only the CCR5 corecepto...

Lung Cancer Classification Employing Proposed Real Coded Genetic Algorithm Based Radial Basis Function Neural Network Classifier.

Computational and mathematical methods in medicine
A proposed real coded genetic algorithm based radial basis function neural network classifier is employed to perform effective classification of healthy and cancer affected lung images. Real Coded Genetic Algorithm (RCGA) is proposed to overcome the ...

The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo I-CLINDE SPECT Imaging: A Test-Retest Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
I-CLINDE is a radiotracer developed for SPECT and targets the 18-kDa translocator protein (TSPO). TSPO is upregulated in glial cells and used as a measure of neuroinflammation in a variety of central nervous system diseases. The aim of this study was...

Using artificial neural networks to select upright cowpea (Vigna unguiculata) genotypes with high productivity and phenotypic stability.

Genetics and molecular research : GMR
Cowpea (Vigna unguiculata) is grown in three Brazilian regions: the Midwest, North, and Northeast, and is consumed by people on low incomes. It is important to investigate the genotype x environment (GE) interaction to provide accurate recommendation...

Using the Generalized Index of Dissimilarity to Detect Gene-Gene Interactions in Multi-Class Phenotypes.

PloS one
To find genetic association between complex diseases and phenotypic traits, one important procedure is conducting a joint analysis. Multifactor dimensionality reduction (MDR) is an efficient method of examining the interactions between genes in genet...

Clustering of soybean genotypes via Ward-MLM and ANNs associated with mixed models.

Genetics and molecular research : GMR
The objectives of this study were to use mixed models to confirm the presence of genetic variability in 16 soybean genotypes, to compare clusters generated by artificial neural networks (ANNs) with those created by the Ward modified location model (M...

Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster.

Genetics
Predicting individual quantitative trait phenotypes from high-resolution genomic polymorphism data is important for personalized medicine in humans, plant and animal breeding, and adaptive evolution. However, this is difficult for populations of unre...