Mass spectrometry (MS)-based proteomics is a disruptive platform in drug discovery that offers an exhaustive view of the proteome's complexity. Focusing on bottom-up MS proteomics, this technology enables high-throughput analysis of protein expressio...
BACKGROUND: Impacted canines are one of the most frequently encountered dental anomalies in maxillofacial practice. Accurate localization of these teeth is crucial for treatment planning, and Cone Beam Computed Tomography (CBCT) offers detailed 3D im...
BACKGROUND: The development of spatial transcriptomics (ST) has enabled biologists to measure transcriptome data on an entire tissue and retain spatial information. It gives us the opportunity to fully understand the tissue microenvironment and ident...
BACKGROUND: An artificial intelligence (AI) pipeline was used to differentiate patients suffering from Chronic Fatigue Syndrome (CFS) from healthy controls (HC) based on high-frequency, large-scale data obtained using beat-to-beat measurement of the ...
Unsustainable mining practices have led to severe ecosystem degradation in mining areas. Ecological restoration plays a crucial role in reinstating the ecosystem service functions of these areas. A monetary evaluation of the ecosystem service value g...
BACKGROUND: Although no definitive treatment exists, 30-40% of postoperative delirium cases are preventable through early risk identification and intervention. Therefore our aim was to develop and evaluate a postoperative delirium risk prediction mod...
BACKGROUND: Multi-drug combinations represent an effective strategy for treating complex diseases. However, due to the vast number of unknown interactions among drugs, accurately predicting drug-drug interactions (DDIs) is essential for preventing ad...
In the digital era, corporate social responsibility (CSR) has become a crucial factor influencing consumer purchase behavior. To investigate the mechanism through which CSR affects customer purchase intention (CPI) and to examine the mediating role o...
Accurate differentiation among asthma, bronchiectasis, and chronic obstructive pulmonary disease (COPD) remains a critical challenge due to overlapping clinical symptoms and limitations of conventional diagnostic tools. This study establishes a trans...
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) pose a significant challenge due to their persistence, bioaccumulation, and multi-system toxicity. Their impact on degenerative diseases, particularly osteoarthritis (OA), remains understudied, nec...
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