AIMC Topic: Immunity, Innate

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Dual-Organ Transcriptomic Analysis of Rainbow Trout Infected With Through Co-Expression and Machine Learning.

Frontiers in immunology
is a major pathogen that causes a high mortality rate in trout farms. However, systemic responses to the pathogen and its interactions with multiple organs during the course of infection have not been well described. In this study, dual-organ transc...

Sensitivity analysis based on the random forest machine learning algorithm identifies candidate genes for regulation of innate and adaptive immune response of chicken.

Poultry science
Two categories of immune responses-innate and adaptive immunity-have both polygenic backgrounds and a significant environmental component. The goal of the reported study was to define candidate genes and mutations for the immune traits of interest in...

Towards the development of robot immune system: A combined approach involving innate immune cells and T-lymphocytes.

Bio Systems
Mobile robots in uncertain and unstructuredenvironments frequently encounter faults. Therefore, an effective fault detection and recovery mechanism is required. One can possibly investigate natural systems to seek inspiration to develop systems that ...

Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.

International journal of molecular sciences
Atherosclerosis is a chronic inflammatory disease characterized by a complex interplay between innate and adaptive immunity. Dendritic cells (DCs) play a key role in T-cell activation and regulation by promoting a tolerogenic environment through the ...

In vitro effects of virgin microplastics on fish head-kidney leucocyte activities.

Environmental pollution (Barking, Essex : 1987)
Microplastics are well-documented pollutants in the marine environment that result from production or fragmentation of larger plastic items. The knowledge about the direct effects of microplastics on immunity, including fish, is still very limited. W...

Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release.

International journal of molecular sciences
Neutrophils are one of the first cells to arrive at the site of infection, where they apply several strategies to kill pathogens: degranulation, respiratory burst, phagocytosis, and release of neutrophil extracellular traps (NETs). Antibiotics have a...

Identification of immune signatures predictive of clinical protection from malaria.

PLoS computational biology
Antibodies are thought to play an essential role in naturally acquired immunity to malaria. Prospective cohort studies have frequently shown how continuous exposure to the malaria parasite Plasmodium falciparum cause an accumulation of specific respo...

Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to .

Frontiers in cellular and infection microbiology
() is problematic for lactating mammals and public health. Understanding of mechanisms by which the hosts respond to severe invasion of remains elusive. In this study, the genome-wide expression of mRNAs and miRNAs in bovine mammary gland cells wer...

Resistance gene identification from Larimichthys crocea with machine learning techniques.

Scientific reports
The research on resistance genes (R-gene) plays a vital role in bioinformatics as it has the capability of coping with adverse changes in the external environment, which can form the corresponding resistance protein by transcription and translation. ...

Screening and preliminary analysis of antimicrobial peptide genes in Octopussinensis.

Fish & shellfish immunology
Antimicrobial peptides (AMPs) are small molecular peptides that widely exist in organisms to resist external microbial invasion and play a crucial role in the host's immune defense system. Owing to their functions of efficient broad-spectrum killing ...