AIMC Topic: Immunoassay

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MoSe Nanolabels for Electrochemical Immunoassays.

Analytical chemistry
There is huge interest in biosensors as a result of the demand for personalized medicine. In biomolecular detection, transition-metal dichalcogenides (TMDs) can be used as signal-enhancing elements. Herein, we utilize a solution-based electrochemical...

Nanocomposites of gold nanoparticles and graphene oxide towards an stable label-free electrochemical immunosensor for detection of cardiac marker troponin-I.

Analytica chimica acta
A stable label-free amperometric immunosensor is presented based on gold nanoparticles and graphene oxide nanocomposites for detection of cardiac troponin-I in the early diagnosis of myocardial infarction. For designing of the sensing platform, first...

A competitive immunoassay for ultrasensitive detection of Hg(2+) in water, human serum and urine samples using immunochromatographic test based on surface-enhanced Raman scattering.

Analytica chimica acta
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg(2+). This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scatterin...

Fabrication of highly catalytic silver nanoclusters/graphene oxide nanocomposite as nanotag for sensitive electrochemical immunoassay.

Analytica chimica acta
Silver nanoclusters and graphene oxide nanocomposite (AgNCs/GRO) is synthesized and functionalized with detection antibody for highly sensitive electrochemical sensing of carcinoembryonic antigen (CEA), a model tumor marker involved in many cancers. ...

A SERS-Assisted 3D Barcode Chip for High-Throughput Biosensing.

Small (Weinheim an der Bergstrasse, Germany)
A surface enhanced Raman scattering (SERS)-assisted 3D barcode chip has been developed for high-throughput biosensing. The 3D barcode is realized through joint 2D spatial encoding with the Raman spectroscopic encoding, which stores the SERS fingerpri...

Slice-Inference-Assisted Lightweight Small Object Detection Model for Holographic Digital Immunoassay Quantification.

Analytical chemistry
Sensitive and cost-effective detection methods utilizing portable equipment are crucial for applications in food safety inspection, environmental monitoring, and clinical diagnosis. In this study, we propose a sliced inference-assisted lightweight sm...

A machine-learning-integrated portable electrochemiluminescence sensing platform for the visualization and high-throughput immunoassays.

Talanta
Electrochemiluminescence (ECL)-based point-of-care testing (POCT) has the potential to facilitate the rapid identification of diseases, offering advantages such as high sensitivity, strong selectivity, and minimal background interference. However, as...

Bioconjugates of photon-upconversion nanoparticles with antibodies for the detection of prostate-specific antigen and p53 in heterogeneous and homogeneous immunoassays.

Nanoscale
Sensitive immunoassays for the detection of tumor biomarkers play an important role in the early diagnosis and therapy of cancer. Using luminescent nanomaterials as labels can significantly improve immunoassay performance, especially in terms of sens...

Data Analysis for Antibody Arrays.

Methods in molecular biology (Clifton, N.J.)
When obtaining high-throughput data from antibody arrays, researchers have to face a couple of questions: How and by what means can they get reasonable results significant to their research from these data? Similar to a gene microarray, the classical...

Precision immunoprofiling to reveal diagnostic signatures for latent tuberculosis infection and reactivation risk stratification.

Integrative biology : quantitative biosciences from nano to macro
Latent tuberculosis infection (LTBI) is estimated in nearly one quarter of the world's population, and of those immunocompetent and infected ~10% will proceed to active tuberculosis (TB). Current diagnostics cannot definitively identify LTBI and prov...