AIMC Topic: Liver
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CFM-UNet: coupling local and global feature extraction networks for medical image segmentation.
Scientific reports
Jul 1, 2025
In medical image segmentation, traditional CNN-based models excel at extracting local features but have limitations in capturing global features. Conversely, Mamba, a novel network framework, effectively captures long-range feature dependencies and e...
Automated quantification of T1 and T2 relaxation times in liver mpMRI using deep learning: a sequence-adaptive approach.
European radiology experimental
Jun 14, 2025
OBJECTIVES: To evaluate a deep learning sequence-adaptive liver multiparametric MRI (mpMRI) assessment with validation in different populations using total and segmental T1 and T2 relaxation time maps.
One-Drop Serum Screening Test to Monitor Tissue Iron Accumulation.
Analytical chemistry
May 30, 2025
Although iron is an essential element for vital body functions, iron overload (IO) is accompanied by significant cellular damage due to its accumulation within organs. Thus, early diagnosis and accurate identification of the affected organs are criti...
Large Scale MRI Collection and Segmentation of Cirrhotic Liver.
Scientific data
May 28, 2025
Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive assessment, accu...
CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.
Free radical biology & medicine
May 23, 2025
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of ef...
Phenylenediamines
Early Growth Response Protein 1
Non-alcoholic Fatty Liver Disease
Gene Expression Regulation
Endoplasmic Reticulum Stress
Disease Models, Animal
Hep G2 Cells
Cyclin-Dependent Kinase Inhibitor p21
Diet, High-Fat
Ferroptosis
Mice, Inbred C57BL
Male
Liver
Mice
Humans
Fatty Liver
Animals
Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos.
Circulation research
May 22, 2025
Over the past few decades, the rising burden of metabolic disease, including type 2 diabetes, prediabetes, obesity, and metabolic dysfunction-associated steatotic liver disease, has corresponded with fundamental shifts in the landscape of heart failu...
Nucleic acid spheres for treating capillarisation of liver sinusoidal endothelial cells in liver fibrosis.
Nature communications
May 15, 2025
Liver sinusoidal endothelial cells (LSECs) lose their characteristic fenestrations and become capillarized during the progression of liver fibrosis. Mesenchymal stem cell (MSC) transplantation can reverse this capillarization and reduce fibrosis, but...
Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images.
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
May 7, 2025
Ultrasound (US) is considered a key modality for the clinical assessment of hepatic steatosis (i.e., fatty liver) due to its noninvasiveness and availability. Deep learning methods have attracted considerable interest in this field, as they are capab...
Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma From Multi-Sequence Magnetic Resonance Imaging Based on Deep Fusion Representation Learning.
IEEE journal of biomedical and health informatics
May 6, 2025
Recent studies have identified microvascular invasion (MVI) as the most vital independent biomarker associated with early tumor recurrence. With advancements in medical technology, several computational methods have been developed to predict preopera...
Assessing the diagnostic accuracy of ChatGPT-4 in the histopathological evaluation of liver fibrosis in MASH.
Hepatology communications
Apr 30, 2025
BACKGROUND: Large language models like ChatGPT have demonstrated potential in medical image interpretation, but their efficacy in liver histopathological analysis remains largely unexplored. This study aims to assess ChatGPT-4-vision's diagnostic acc...
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