AIMC Topic: Lymphatic Metastasis

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L1 Cell Adhesion Molecule and Its Soluble Form sL1 Exhibit Poor Prognosis in Primary Breast Cancer Patients.

Clinical breast cancer Dec 28, 2017
INTRODUCTION: The L1 cell adhesion molecule (L1-CAM) and its soluble form sL1 play a prominent role in invasion and metastasis in several cancers. However, its association with breast cancer is still unclear.
Lymphatic Metastasis Humans Adult Breast Neoplasms Disease-Free Survival Prognosis Biomarkers, Tumor Cell Membrane Female Middle Aged Cytoplasm Aged Disease Progression Neural Cell Adhesion Molecule L1 Aged, 80 and over
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The utility of sentinel lymph node mapping in the management of endometrial atypical hyperplasia.

Gynecologic oncology Dec 28, 2017
OBJECTIVES: To determine the risk of endometrial cancer (EC) and lymph node involvement in patients with a preoperative diagnosis of "AH-only" versus "AH - cannot rule out carcinoma" and to study the value of SLN mapping.
Predictive Value of Tests Humans Female Aged Aged, 80 and over Adult Sensitivity and Specificity Neoplasm Staging Neoplasm Grading Pelvis Endometrial Neoplasms Middle Aged Membrane Proteins Lymphatic Metastasis Neoplasm Invasiveness Lymph Node Excision CA-125 Antigen Carcinoma, Endometrioid Endometrial Hyperplasia Myometrium Sentinel Lymph Node Biopsy
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Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study.

BMC pulmonary medicine Dec 28, 2017
BACKGROUND: Previous studies show that overexpression of EMMPRIN involved in the malignant biological behavior of tumors. This investigation was to disclose the expression status of EMMPRIN in non-small cell lung cancer (NSCLC) and its clinical value...
Humans Retrospective Studies Female Risk Factors Biomarkers, Tumor Male Middle Aged ROC Curve Lung Neoplasms Immunohistochemistry Gene Expression Regulation, Neoplastic Up-Regulation Lymph Nodes Basigin Carcinoma, Non-Small-Cell Lung Lymphatic Metastasis Neoplasm Staging
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Artificial intelligence may help in predicting the need for additional surgery after endoscopic resection of T1 colorectal cancer.

Endoscopy Dec 22, 2017
BACKGROUND AND STUDY AIMS: Decisions concerning additional surgery after endoscopic resection of T1 colorectal cancer (CRC) are difficult because preoperative prediction of lymph node metastasis (LNM) is problematic. We investigated whether artificia...
Japan Unnecessary Procedures Risk Assessment Humans Models, Theoretical Artificial Intelligence Lymphatic Metastasis Prognosis Neoplasm Staging Female Heuristics Aged Sensitivity and Specificity Endoscopy Colorectal Neoplasms Diagnostic Errors Male Middle Aged
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Metastasis detection from whole slide images using local features and random forests.

Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr 20, 2017
Digital pathology has led to a demand for automated detection of regions of interest, such as cancerous tissue, from scanned whole slide images. With accurate methods using image analysis and machine learning, significant speed-up, and savings in cos...
Humans Machine Learning Software Female Adult Breast Neoplasms Lymphocytes Image Interpretation, Computer-Assisted Cell Nucleus Histocytochemistry Eosine Yellowish-(YS) Hematoxylin Middle Aged ROC Curve Lymph Nodes Lymphatic Metastasis Area Under Curve
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Extended versus standard pelvic lymphadenectomy during robot-assisted radical prostatectomy: the role of extended template as an independent predictor of lymph node invasion with comparable morbidity burden.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology Mar 10, 2017
BACKGROUND: To assess oncologic and surgical outcomes in patients subjected to standard (S) versus extended (E) pelvic lymph node dissection (PLND) during robot-assisted radical prostatectomy (RARP).
Humans Robotics Prognosis Prostatic Neoplasms Aged Middle Aged Male Neoplasm Grading Postoperative Complications Pelvis Cohort Studies Prostatectomy Treatment Outcome Lymphatic Metastasis Lymph Node Excision
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Patterns of Recurrence After Postprostatectomy Fossa Radiation Therapy Identified by C-11 Choline Positron Emission Tomography/Computed Tomography.

International journal of radiation oncology, biology, physics Nov 17, 2016
PURPOSE: To evaluate C-11 choline positron emission tomography/computed tomography (CholPET) in staging and determining patterns of recurrence in prostate cancer patients with rising prostate-specific antigen levels after prostatectomy radiation ther...
Male Prostatectomy Middle Aged Statistics, Nonparametric Lymphatic Metastasis Viscera Bone Neoplasms Carbon Radioisotopes Humans Postoperative Care Positron Emission Tomography Computed Tomography Aged Prostatic Neoplasms Prostate-Specific Antigen Neoplasm Grading Neoplasm Recurrence, Local Choline
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Preoperative assessment of lymph node metastasis in endometrial cancer: A Korean Gynecologic Oncology Group study.

Cancer Nov 7, 2016
BACKGROUND: Previously proposed criteria for preoperatively identifying endometrial cancer patients at low risk for lymph node metastasis remain to be verified. For this purpose, a prospective, multicenter observational study was performed.
Aged Aged, 80 and over Adult Sensitivity and Specificity Middle Aged Humans Prospective Studies Female Pelvis Endometrial Neoplasms CA-125 Antigen Preoperative Period Lymph Nodes Lymphatic Metastasis Magnetic Resonance Imaging Lymph Node Excision Uterus
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Sentinel Lymph Node Dissection to Select Clinically Node-negative Prostate Cancer Patients for Pelvic Radiation Therapy: Effect on Biochemical Recurrence and Systemic Progression.

International journal of radiation oncology, biology, physics Oct 19, 2016
PURPOSE: To assess the efficacy of robotic-assisted laparoscopic sentinel lymph node (SLN) dissection (SLND) to select those patients with prostate cancer (PCa) who would benefit from additional pelvic external beam radiation therapy and long-term an...
Sentinel Lymph Node Biopsy Lymphatic Irradiation Lymphatic Metastasis Prostatic Neoplasms Neoplasm Staging Prostate-Specific Antigen Robotic Surgical Procedures Pelvis Androgen Antagonists Neoplasm Recurrence, Local Patient Selection Radiotherapy, Conformal Statistics, Nonparametric Aged Male Middle Aged Disease Progression Nomograms Humans
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Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis.

Scientific reports May 23, 2016
Pathologists face a substantial increase in workload and complexity of histopathologic cancer diagnosis due to the advent of personalized medicine. Therefore, diagnostic protocols have to focus equally on efficiency and accuracy. In this paper we int...
Humans Neural Networks, Computer Histological Techniques Machine Learning Female Breast Neoplasms Male Diagnosis, Computer-Assisted Lymphatic Metastasis Prostatic Neoplasms Neoplasm Staging Image Interpretation, Computer-Assisted Sentinel Lymph Node Biopsy
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