AIMC Topic: Macrophages
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Isolation and identification of immunomodulatory selenium-containing peptides from selenium-enriched rice protein hydrolysates.
Food chemistry
Sep 20, 2018
The RAW264.7 cell model was employed to screen immunomodulatory selenium-containing peptides from selenium-enriched rice protein hydrolysates (SPHs). Moreover, the selenium-containing peptides of high-activity protein hydrolysates were purified by Se...
Explaining the dynamics of tumor aggressiveness: At the crossroads between biology, artificial intelligence and complex systems.
Seminars in cancer biology
Jul 11, 2018
Facing metastasis is the most pressing challenge of cancer research. In this review, we discuss recent advances in understanding phenotypic plasticity of cancer cells, highlighting the kinetics of cancer stem cell and the role of the epithelial mesen...
Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential.
Journal of food and drug analysis
Jul 2, 2018
Acacia catechu L., (Fabaceae) named as "catechu" is a plant, the decoction of heartwood of which is daily consumed as thirst quencher by a good percentage of the population in South India. The plant is mainly distributed in India and other Asian coun...
Gastro-protective effect of edible plant Artemisia argyi in ethanol-induced rats via normalizing inflammatory responses and oxidative stress.
Journal of ethnopharmacology
Dec 20, 2017
PHARMACOLOGICAL RELEVANCE: Artemisia argyi, a kind of ethnic drug, has a long-term use on gastric diseases and syndromes.
Anti-Inflammatory Agents
Artemisia
Plants, Medicinal
Inflammation Mediators
RAW 264.7 Cells
Free Radicals
Cytoprotection
Phytotherapy
Malondialdehyde
Macrophages
Superoxide Dismutase
Animals
Ethanol
Mice
Oxidative Stress
Anti-Ulcer Agents
Disease Models, Animal
Antioxidants
Gastric Mucosa
Plant Extracts
Stomach Ulcer
Rats, Wistar
Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.
Biochemical and biophysical research communications
Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
Image based Machine Learning for identification of macrophage subsets.
Scientific reports
Jun 14, 2017
Macrophages play a crucial rule in orchestrating immune responses against pathogens and foreign materials. Macrophages have remarkable plasticity in response to environmental cues and are able to acquire a spectrum of activation status, best exemplif...
Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties.
European journal of medicinal chemistry
May 1, 2017
A new family of imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxide with antiproliferative Trypanosoma cruzi properties was identified from a neural network model published by our group. The synthesis and evaluation of this new class of trypanocidal agents ...
Hybrid-Actuating Macrophage-Based Microrobots for Active Cancer Therapy.
Scientific reports
Jun 27, 2016
Using macrophage recruitment in tumors, we develop active, transportable, cancer theragnostic macrophage-based microrobots as vector to deliver therapeutic agents to tumor regions. The macrophage-based microrobots contain docetaxel (DTX)-loaded poly-...
An immune-inspired swarm aggregation algorithm for self-healing swarm robotic systems.
Bio Systems
May 10, 2016
Swarm robotics is concerned with the decentralised coordination of multiple robots having only limited communication and interaction abilities. Although fault tolerance and robustness to individual robot failures have often been used to justify the u...
Investigation of the mutagenic and genotoxic activities of LLL-3, a STAT3 inhibitor.
Drug and chemical toxicology
Apr 10, 2016
LLL-3, an anthracene derived compound, has been shown to be a promising therapeutic agent for the treatment of some kinds of cancer such as chronic myeloid leukemia and glioblastoma. However, no data regarding the toxic properties of this compound ha...
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