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Ultrasonic liver steatosis quantification by a learning-based acoustic model from a novel shear wave sequence.

Biomedical engineering online
BACKGROUND: An efficient and accurate approach to quantify the steatosis extent of liver is important for clinical practice. For the purpose, we propose a specific designed ultrasound shear wave sequence to estimate ultrasonic and shear wave physical...

Prostate Cancer Detection using Deep Convolutional Neural Networks.

Scientific reports
Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has been intens...

Accurate Deep Learning-Based Sleep Staging in a Clinical Population With Suspected Obstructive Sleep Apnea.

IEEE journal of biomedical and health informatics
The identification of sleep stages is essential in the diagnostics of sleep disorders, among which obstructive sleep apnea (OSA) is one of the most prevalent. However, manual scoring of sleep stages is time-consuming, subjective, and costly. To overc...

Efficient identification of novel anti-glioma lead compounds by machine learning models.

European journal of medicinal chemistry
Glioblastoma multiforme (GBM) is the most devastating and widespread primary central nervous system tumor. Pharmacological treatment of this malignance is limited by the selective permeability of the blood-brain barrier (BBB) and relies on a single d...

Hypergraph based multi-task feature selection for multimodal classification of Alzheimer's disease.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Multi-modality based classification methods are superior to the single modality based approaches for the automatic diagnosis of the Alzheimer's disease (AD) and mild cognitive impairment (MCI). However, most of the multi-modality based methods usuall...

Deep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade Gliomas.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Patient survival in high-grade glioma remains poor, despite the recent developments in cancer treatment. As new chemo-, targeted molecular, and immune therapies emerge and show promising results in clinical trials, image-based...

A hybrid automated treatment planning solution for esophageal cancer.

Radiation oncology (London, England)
OBJECTIVE: This study aims to investigate a hybrid automated treatment planning (HAP) solution that combines knowledge-based planning (KBP) and script-based planning for esophageal cancer.