Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Sep 1, 2025
BACKGROUND: Neoadjuvant chemoradiotherapy is a standard treatment for locally advanced rectal cancer, but acute diarrhoea remains a significant side effect, affecting the completion of chemoradiotherapy treatment.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Sep 1, 2025
BACKGROUND AND PURPOSE: This study investigates the use of Vision Transformers (ViTs) to predict Freedom from Local Failure (FFLF) in patients with brain metastases using pre-operative MRI scans. The goal is to develop a model that enhances risk stra...
BACKGROUND: Considerable evidence highlights the intricate association between liquid-liquid phase separation (LLPS) and tumorigenesis, progression, and therapy resistance. However, there has been limited exploration of the role of LLPS in hepatoblas...
Inflammatory responses play a crucial role in the progression of pediatric neurogenic bladder (NB)-associated fibrosis; however, their specific contributions remain poorly understood. This study aimed to identify inflammation-related biomarkers for d...
Ecotoxicology and environmental safety
Sep 1, 2025
Our aim is to evaluate the association of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) with offspring blood pressure (BP); examine the moderating effect of children's age; and the mediating effects of inflammatory cytokines. Data o...
European journal of clinical pharmacology
Sep 1, 2025
PURPOSE: This study develops and compares population pharmacokinetics (PopPK) models and machine learning methods, including neural networks, to predict steady-state trough concentrations in pediatric patients and provide improved dosing recommendati...
AIM: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are closely intertwined comorbidities that present significant clinical challenges due to the poorly understood pathophysiological mechanisms driving their coexistence. In this ...
Accurately predicting cognitive scores based on structural MRI holds significant clinical value for understanding the pathological stages of dementia and forecasting Alzheimer's disease (AD). Some existing deep learning methods often depend on anatom...
BACKGROUND: Sleep apnea (SA), a prevalent sleep-related breathing disorder, disrupts normal respiratory patterns during sleep. This disruption can have a cascading effect on the body, potentially leading to complications in various organs, including ...
Respiratory and cardiovascular diseases represent a significant global health burden, underscoring the need for innovative, accessible, and cost-effective screening solutions. This study introduces a clinically grounded framework for the early detect...
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