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MicroRNAs

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The integrative knowledge base for miRNA-mRNA expression in colorectal cancer.

Scientific reports
"miRNA colorectal cancer" (https://mirna-coadread.omics.si/) is a freely available web application for studying microRNA and mRNA expression and their correlation in colorectal cancer. To the best of our knowledge, "miRNA colorectal cancer" has the l...

DeepMiR2GO: Inferring Functions of Human MicroRNAs Using a Deep Multi-Label Classification Model.

International journal of molecular sciences
MicroRNAs (miRNAs) are a highly abundant collection of functional non-coding RNAs involved in cellular regulation and various complex human diseases. Although a large number of miRNAs have been identified, most of their physiological functions remain...

[Expression of plasma microRNA in patients with acromegaly].

Problemy endokrinologii
BACKGROUND: microRNA is a class of small non-coding RNA molecules involved in posttranscriptional regulation of gene expression. MicroRNAs are detectable in blood in stable concentrations, which makes them promising biomarkers for various diseases.

Approach for the Definition of radiomiRNomic Signatures for Breast Cancer Differential Diagnosis.

International journal of molecular sciences
UNLABELLED: Personalized medicine relies on the integration and consideration of specific characteristics of the patient, such as tumor phenotypic and genotypic profiling.

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data.

BMC medical genomics
BACKGROUND: Dementia with Lewy bodies (DLB) is the second most common subtype of neurodegenerative dementia in humans following Alzheimer's disease (AD). Present clinical diagnosis of DLB has high specificity and low sensitivity and finding potential...

A semi-supervised machine learning framework for microRNA classification.

Human genomics
BACKGROUND: MicroRNAs (miRNAs) are a family of short, non-coding RNAs that have been linked to critical cellular activities, most notably regulation of gene expression. The identification of miRNA is a cross-disciplinary approach that requires both c...

Study on miR-384-5p activates TGF-β signaling pathway to promote neuronal damage in abutment nucleus of rats based on deep learning.

Artificial intelligence in medicine
BACKGROUND: Any ailment in our organs can be visualized by using different modality signals and images. Hospitals are encountering a massive influx of large multimodality patient data to be analysed accurately and with context understanding. The deep...

Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection.

BMC bioinformatics
BACKGROUND: MicroRNAs (miRNAs) are noncoding RNA molecules heavily involved in human tumors, in which few of them circulating the human body. Finding a tumor-associated signature of miRNA, that is, the minimum miRNA entities to be measured for discri...

LDAPred: A Method Based on Information Flow Propagation and a Convolutional Neural Network for the Prediction of Disease-Associated lncRNAs.

International journal of molecular sciences
Long non-coding RNAs (lncRNAs) play a crucial role in the pathogenesis and development of complex diseases. Predicting potential lncRNA-disease associations can improve our understanding of the molecular mechanisms of human diseases and help identify...

Integration of Cancer Genomics Data for Tree-based Dimensionality Reduction and Cancer Outcome Prediction.

Molecular informatics
Accurate outcome prediction is crucial for precision medicine and personalized treatment of cancer. Researchers have found that multi-dimensional cancer omics studies outperform each data type (mRNA, microRNA, methylation or somatic copy number alter...