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Development of a chitosanase 3-like protein 1 assay kit and study of its application in patients with hepatocellular carcinoma.
BMC biotechnology
May 12, 2025
OBJECTIVE: The detection kit for plasma Chitinase-3-like Protein 1 was developed using the magnetic bead chemiluminescence method, in order to investigate the diagnostic value of DD, FDP, CHI3L1, AFP-L3 and PIVKA-II in hepatocellular carcinoma.
Minimum clinically important difference in Quantitative Lung Fibrosis score associated with all-cause mortality in idiopathic pulmonary fibrosis: subanalysis from two phase II trials of pamrevlumab.
BMJ open
May 12, 2025
OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease. Chest high-resolution CT (HRCT) is instrumental in IPF management, and the Quantitative Lung Fibrosis (QLF) score is a computer-assisted metric for quantifyin...
Reinforcement Learning-Driven Path Generation for Ankle Rehabilitation Robot Using Musculoskeletal-Informed Energy Optimization.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
May 12, 2025
In rehabilitation robotics, optimizing energy consumption and high interaction forces is essential to prevent unnecessary muscle fatigue and excessive joint loading as they often cause an inefficient trajectory planning and disrupt natural movement p...
High procalcitonin level is related to blood stream infections, gram-negative pathogens, and ICU admission in infections of adult febrile cancer patients.
Journal of the Egyptian National Cancer Institute
May 10, 2025
BACKGROUND: Blood stream infection (BSI) represent a life-threatening condition. Thus, we aimed to investigate the role of procalcitonin (PCT) and C-reactive protein (CRP) tests in adult febrile patients with BSI and other clinical infections in hosp...
Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.
Journal of translational medicine
May 9, 2025
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
Water intake, hydration status and cognitive functions in older adults - a pilot study.
European journal of nutrition
May 9, 2025
PURPOSE: This study aimed to assess the relationship between the hydration status and cognitive functioning of older adults. The novelty of the study was the simultaneous use of several indicators of hydration status, including plasma and urine osmol...
Improving lower-extremity artery depiction and diagnostic confidence using dual-energy technique and popliteal artery monitoring in dual-low dose CT angiography.
Scientific reports
May 9, 2025
To assess the utility of dual-energy CT scanning (DECTs) with popliteal artery (PA) monitoring in dual low-dose (radiation and contrast) lower-extremity CT angiography (LE-CTA). 135 patients undergoing LE-CTA were prospectively included and divided i...
Development and validation of a collaborative framework for assessment of peripheral facial paralysis using facial image regions of interest.
Acta oto-laryngologica
May 8, 2025
BACKGROUND: While accurate evaluation of PFP is crucial for determining optimal treatment strategies, current clinical assessments rely heavily on subjective evaluations, leading to considerable variability between inter- and intra-observer ratings.
Gait Characteristics Associated with Walking Speed in Postoperative Patients with Adult Spinal Deformity Extracted by Machine Learning.
Annals of biomedical engineering
May 8, 2025
PURPOSE: Patients with adult spinal deformity (ASD) are unable to walk faster even after spinal fixation. Gait rehabilitation that focuses on movements associated with reduced speed may help improve gait function. This study aimed to identify the gai...
A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.
Scientific reports
May 8, 2025
This study aimed to demonstrate whether plasma galectin-3 could predict the development of postoperative delirium (POD) in patients with acute aortic dissection (AAD). Prospective, observational study. Cardiac surgery intensive care unit. Consecutive...
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