BACKGROUND: PD-1/PD-L1 immunotherapy represents the primary treatment for advanced NSCLC patients; however, response rates to this therapy vary among individuals. This dual-center study aimed to integrate habitat radiomics and multi-instance deep lea...
Fat and muscle mass are potential biomarkers of wellbeing and disease in oncology, but clinical measurement methods vary considerably. Here we evaluate the accuracy, precision and ability to track change for multiple deep learning (DL) models that qu...
Elevated postprandial glucose levels present a global epidemic and a major challenge in type-2 diabetes (T2D) management. A key barrier to developing effective dietary interventions for T2D management is the wide inter-individual variation in glycemi...
BACKGROUND: Traditional ocular gaze photograph preprocessing, relying on manual cropping and head tilt correction, is time-consuming and inconsistent, limiting artificial intelligence (AI) model development and clinical application.
BACKGROUND: Early detection of depression is crucial for implementing interventions. Deep learning-based computer vision (CV), semantic, and acoustic analysis have enabled the automated analysis of visual and auditory signals.
Extracellular vesicles (EVs) exhibit extensive glycosylation modifications, which are promising biomarkers for gastric cancer (GC). However, EV glycomics and the potential application of EV glycosylation patterns in liquid biopsy remain largely unexp...
BACKGROUND: Few individuals with alcohol use disorder (AUD) receive treatment. Previous studies have shown drinking behavior, psychological problems, and substance dependence to predict treatment seeking. However, to date, no studies have incorporate...
The journal of prevention of Alzheimer's disease
Jul 16, 2025
BACKGROUND: Alzheimer's disease (AD) frequently co-occurs with depressive symptoms, exacerbating both cognitive decline and clinical complexity, yet the neural substrates linking this co-occurrence remain poorly understood. We aimed to investigate th...
PURPOSE: Late Gadolinium Enhancement (LGE) images are crucial elements of CMR protocols for evaluating myocardial infarct (MI) severity and size. However, these images rely on signal intensity changes and manual inversion time (TI) settings, leading ...
Journal of the American College of Surgeons
Jul 16, 2025
BACKGROUND: Financial toxicity (FT) refers to the financial stress and detrimental impact on quality of life experienced by patients due to treatment cost. In patients with resected lung cancer (LC), we sought to identify those at risk of developing ...
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