AIMC Topic: Myocardium

Clear Filters Showing 81 to 90 of 109 articles

Neural-network classification of cardiac disease from P cardiovascular magnetic resonance spectroscopy measures of creatine kinase energy metabolism.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
BACKGROUND: The heart's energy demand per gram of tissue is the body's highest and creatine kinase (CK) metabolism, its primary energy reserve, is compromised in common heart diseases. Here, neural-network analysis is used to test whether noninvasive...

Using machine learning to characterize heart failure across the scales.

Biomechanics and modeling in mechanobiology
Heart failure is a progressive chronic condition in which the heart undergoes detrimental changes in structure and function across multiple scales in time and space. Multiscale models of cardiac growth can provide a patient-specific window into the p...

Smeared multiscale finite element model for electrophysiology and ionic transport in biological tissue.

Computers in biology and medicine
Basic functions of living organisms are governed by the nervous system through bidirectional signals transmitted from the brain to neural networks. These signals are similar to electrical waves. In electrophysiology the goal is to study the electrica...

An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
BACKGROUND: We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate rejection. In the present study we ex...

Automated selection of myocardial inversion time with a convolutional neural network: Spatial temporal ensemble myocardium inversion network (STEMI-NET).

Magnetic resonance in medicine
PURPOSE: Delayed enhancement imaging is an essential component of cardiac MRI, which is used widely for the evaluation of myocardial scar and viability. The selection of an optimal inversion time (TI) or null point (TI ) to suppress the background my...

Automated analysis of cardiovascular magnetic resonance myocardial native T mapping images using fully convolutional neural networks.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
BACKGROUND: Cardiovascular magnetic resonance (CMR) myocardial native T mapping allows assessment of interstitial diffuse fibrosis. In this technique, the global and regional T are measured manually by drawing region of interest in motion-corrected T...

Serum Peroxisome Proliferator-activated Receptor Gamma Coactivator-1α Related to Myocardial Energy Expenditure in Patients With Chronic Heart Failure.

The American journal of the medical sciences
BACKGROUND: Peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) plays key roles in controlling cardiac metabolism and function. Myocardial energy expenditure (MEE) can reflect myocardial energy metabolism and cardiac function. Wh...

Hypertonic Saline Modulates Heart Function and Myocardial Inflammatory Alterations in Brain-Dead Rats.

The Journal of surgical research
BACKGROUND: Brain death (BD) in potential organ donors is responsible for hemodynamic instability and organ hypoperfusion, leading to myocardial dysfunction. Hypertonic saline (HS) is a volume expander with positive effects on hemodynamics and immuno...

Detection of nanodiamonds in biological samples by EPR spectrometry.

Doklady. Biochemistry and biophysics
In model experiments in vitro, the applicability of the EPR spectrometry method for the detection of modified nanodiamonds (MNDs) in blood and homogenates of mouse organs has been established. A characteristic signal (g = 2.003, ΔH ≈ 10 G) is observe...