AIMC Topic: Osteoarthritis
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A web-based system for neural network based classification in temporomandibular joint osteoarthritis.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
May 1, 2018
OBJECTIVE: The purpose of this study is to describe the methodological innovations of a web-based system for storage, integration and computation of biomedical data, using a training imaging dataset to remotely compute a deep neural network classifie...
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data.
Arthritis & rheumatology (Hoboken, N.J.)
Apr 2, 2018
OBJECTIVE: In this study, we sought to refine histologic scoring of rheumatoid arthritis (RA) synovial tissue by training with gene expression data and machine learning.
Deep transfer learning for characterizing chondrocyte patterns in phase contrast X-Ray computed tomography images of the human patellar cartilage.
Computers in biology and medicine
Feb 9, 2018
Phase contrast X-ray computed tomography (PCI-CT) has been demonstrated to be effective for visualization of the human cartilage matrix at micrometer resolution, thereby capturing osteoarthritis induced changes to chondrocyte organization. This study...
Platelet-rich plasma inhibits Wnt/β-catenin signaling in rabbit cartilage cells activated by IL-1β.
International immunopharmacology
Dec 30, 2017
OBJECTIVE: Platelet-rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/β-catenin signaling in rabbit chondrocytes.
Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-B Pathway.
BioMed research international
Dec 3, 2017
BACKGROUND: Garlic-derived S-allylmercaptocysteine (SAMC) has widely been used in many disease therapies. However, the potential effects and mechanism of SAMC on IL-1-stimulated chondrocytes are unclear.
Handling limited datasets with neural networks in medical applications: A small-data approach.
Artificial intelligence in medicine
Jan 2, 2017
MOTIVATION: Single-centre studies in medical domain are often characterised by limited samples due to the complexity and high costs of patient data collection. Machine learning methods for regression modelling of small datasets (less than 10 observat...
Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.
Journal of clinical anesthesia
Dec 22, 2016
STUDY OBJECTIVES: Pain after total knee replacement (TKR) interferes with early rehabilitation. Although the use of epidural bupivacaine in post-TKR patients is associated with effective analgesia, the associated motor blockade effect delays function...
Pain Measurement
Double-Blind Method
Pain, Postoperative
Bupivacaine
Ropivacaine
Analgesics, Opioid
Fentanyl
Osteoarthritis
Drug Combinations
Amides
Postoperative Care
Nausea
Aged
Anesthetics, Local
Analgesia, Patient-Controlled
Analgesia, Epidural
Humans
Male
Arthroplasty, Replacement, Knee
Prospective Studies
Middle Aged
Pain Management
Female
Treatment Outcome
Patient Satisfaction
A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear.
The American journal of sports medicine
Oct 7, 2016
BACKGROUND: It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. A growing body of evidence strongly suggests that the progression f...
Classification of sodium MRI data of cartilage using machine learning.
Magnetic resonance in medicine
Nov 3, 2014
PURPOSE: To assess the possible utility of machine learning for classifying subjects with and subjects without osteoarthritis using sodium magnetic resonance imaging data. Theory: Support vector machine, k-nearest neighbors, naïve Bayes, discriminant...
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types.
Computers in biology and medicine
Jul 1, 2025
Considering the high incidence of osteoarthritis (OA), especially of the knee and hip, this study explores the possible genetic associations between OA and cancer types, including cancers of the bladder, kidney, breast, and prostate. The objective of...
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