AIMC Topic: Osteogenesis

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Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Biochemical and biophysical research communications Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
Dose-Response Relationship, Drug NF-kappa B RAW 264.7 Cells Osteoblasts Osteogenesis Cells, Cultured Macrophages Animals Signal Transduction RANK Ligand Mice Mice, Inbred C57BL Glycosides
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Structural characterization and osteogenic bioactivity of a sulfated polysaccharide from pacific abalone (Haliotis discus hannai Ino).

Carbohydrate polymers Nov 6, 2017
Bone morphogenic protein-2 (BMP-2) is known to promote osteogenesis. To find novel adjuvants to enhance the activity of BMP-2, the present study investigated the structure BMP-2-induced osteogenic activity of a water-soluble polysaccharide from the g...
Bone Morphogenetic Protein 2 Molecular Structure Polysaccharides Sulfates Gastropoda Animals Osteogenesis Cells, Cultured Mice Dose-Response Relationship, Drug
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Effect of Short-Term Stimulation with Interleukin-1β and Differentiation Medium on Human Mesenchymal Stromal Cell Paracrine Activity in Coculture with Osteoblasts.

BioMed research international Dec 22, 2015
INTRODUCTION: Human mesenchymal stromal cells (hMSCs) exhibit the potential to accelerate bone healing by enhanced osteogenic differentiation. Interleukin-1β is highly expressed during fracture healing and has been demonstrated to exert a significant...
Male Middle Aged Time Factors Female Adult Osteosarcoma Cell Differentiation Interleukin-1beta Cell Line, Tumor Culture Media Humans Paracrine Communication Osteogenesis Coculture Techniques Mesenchymal Stem Cells Gene Expression Regulation Osteoblasts
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[Advances in mechanotransduction signaling pathways in distraction osteogenesis].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery Jul 15, 2025
OBJECTIVE: To review the role and research progress of mechanotransduction signaling pathway in distraction osteogenesis, so as to provide theoretical basis and reference for clinical treatment.
beta Catenin Bone Regeneration Osteoblasts Transforming Growth Factor beta Osteogenesis Integrins Ion Channels Mechanotransduction, Cellular Smad Proteins Humans Bone Morphogenetic Proteins Signal Transduction Animals Osteogenesis, Distraction
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[Naringenin promotes osteogenic differentiation of BMSCs via SDF-1α/CXCR4 signaling axis].

Shanghai kou qiang yi xue = Shanghai journal of stomatology Dec 1, 2021
PURPOSE: To explore the influence of naringenin on osteogenic differentiation of bone mesenchymal stem cells(BMSCs), and the role of SDF-1α/CXCR4 signaling axis in the osteogenic differentiation by naringenin.
Receptors, CXCR4 Cell Differentiation Bone Marrow Cells Flavanones Osteogenesis Cells, Cultured RNA, Messenger Rats Animals Chemokine CXCL12
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[Effect of TNF-α on the ability of stem cells from human exfoliated deciduous teeth to promote osteoclastogenesis].

Shanghai kou qiang yi xue = Shanghai journal of stomatology Oct 1, 2018
PURPOSE: To investigate the effect of tumor necrosis factor-α (TNF-α) on the ability of stem cells from human exfoliated deciduous teeth (SHED) to promote osteoclastogenesis.
Cells, Cultured Tooth, Deciduous Leukocytes, Mononuclear NF-kappa B Stem Cells Humans Osteogenesis Tumor Necrosis Factor-alpha
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Osteoinductive Activity of DFDBA Materials versus Growth Factors on Gene Expression of MG-63 Cells: An In Vitro Study.

Journal of long-term effects of medical implants Jan 1, 2016
Guided bone regeneration using demineralized freeze-dried bone allograft (DFDBA) and growth factors (GFs) is a current goal in implant dentistry because of their potential osteoinductive abilities. Regarding controversial results, the purpose of this...
Osteogenesis Bone Transplantation Platelet-Derived Growth Factor Osteoblasts Cell Line, Tumor Cell Differentiation Transforming Growth Factor beta Humans
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