BACKGROUND: Parkinson's disease is a movement disorder featuring motor symptoms and cognitive decline, which can manifest as mild cognitive impairment. The incidence of mild cognitive impairment increases with disease progression, and Parkinson's dis...
To evaluate the impact of various magnetic resonance imaging (MRI) preprocessing methods on radiomic feature reproducibility and classification performance in differentiating Parkinson's disease (PD) motor subtypes. We analyzed 210 T1-weighted MRI sc...
BACKGROUND: There is a growing need for alternative imaging measures to better understand the neurodegenerative pathology of Parkinson's disease and related conditions, such as drug-induced Parkinsonism. This study investigated the link between optic...
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including gait impairments, which significantly affect patient mobility and quality of life. An accurate assessment of the severity of PD is crucial for clinica...
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by a wide spectrum of motor and non-motor symptoms, often leading to delayed or inaccurate diagnosis. Conventional diagnostic methods frequently suffer from limited se...
The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of the brain. In humans, it is essential for coordinating sensorimotor responses and performing associative or executive functions. Identifying which ge...
OBJECTIVE: Freezing of gait (FOG) is a common gait disorder in the advanced stages of Parkinson's disease (PD), closely associated with impaired balance and executive function. This study aimed to investigate specific changes in brain glucose metabol...
Parkinson's disease (PD) is a progressive neurological disorder that affects millions globally, posing significant challenges in early and accurate diagnosis. Recent advancements in machine learning (ML) offer promising approaches for addressing thes...
Journal of neuroengineering and rehabilitation
Oct 22, 2025
BACKGROUND: Electroencephalogram (EEG) microstates provide insights into large-scale brain network coordination, revealing distinct neural dynamics within specific frequency bands associated with cognitive processes and neurological disorders. Critic...
Parkinson's disease (PD) causes motor, non-motor, and mental health challenges that significantly impact health-related quality of life (HRQoL); however, previous studies relied on subjective assessments. Several factors are associated with poor HRQo...
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