AIMC Topic: Patient Selection

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Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data.

Scientific reports
Conventional inclusion criteria used in osteoarthritis clinical trials are not very effective in selecting patients who would benefit from a therapy being tested. Typically majority of selected patients show no or limited disease progression during a...

Cohort selection for clinical trials using multiple instance learning.

Journal of biomedical informatics
Identifying patients eligible for clinical trials using electronic health records (EHRs) is a challenging task usually requiring a comprehensive analysis of information stored in multiple EHRs of a patient. The goal of this study is to investigate di...

Natural Language Processing for Mimicking Clinical Trial Recruitment in Critical Care: A Semi-Automated Simulation Based on the LeoPARDS Trial.

IEEE journal of biomedical and health informatics
Clinical trials often fail to recruit an adequate number of appropriate patients. Identifying eligible trial participants is resource-intensive when relying on manual review of clinical notes, particularly in critical care settings where the time win...

Applying Machine Learning in Liver Disease and Transplantation: A Comprehensive Review.

Hepatology (Baltimore, Md.)
Machine learning (ML) utilizes artificial intelligence to generate predictive models efficiently and more effectively than conventional methods through detection of hidden patterns within large data sets. With this in mind, there are several areas wi...

Artificial intelligence in abdominal aortic aneurysm.

Journal of vascular surgery
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a life-threatening disease, and the only curative treatment relies on open or endovascular repair. The decision to treat relies on the evaluation of the risk of AAA growth and rupture, which can be diffic...

Patient selection for proton therapy: a radiobiological fuzzy Markov model incorporating robust plan analysis.

Physical and engineering sciences in medicine
While proton therapy can offer increased sparing of healthy tissue compared with X-ray therapy, it can be difficult to predict whether a benefit can be expected for an individual patient. Predictive modelling may aid in this respect. However, the pre...