AIMC Topic:
Predictive Value of Tests

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Validation of deep-learning image reconstruction for coronary computed tomography angiography: Impact on noise, image quality and diagnostic accuracy.

Journal of cardiovascular computed tomography
BACKGROUND: Advances in image reconstruction are necessary to decrease radiation exposure from coronary CT angiography (CCTA) further, but iterative reconstruction has been shown to degrade image quality at high levels. Deep-learning image reconstruc...

Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.

The Lancet. Oncology
BACKGROUND: An increasing volume of prostate biopsies and a worldwide shortage of urological pathologists puts a strain on pathology departments. Additionally, the high intra-observer and inter-observer variability in grading can result in overtreatm...

Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study.

The Lancet. Oncology
BACKGROUND: The Gleason score is the strongest correlating predictor of recurrence for prostate cancer, but has substantial inter-observer variability, limiting its usefulness for individual patients. Specialised urological pathologists have greater ...

High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets.

Cancer immunology research
Computational prediction of binding between neoantigen peptides and major histocompatibility complex (MHC) proteins can be used to predict patient response to cancer immunotherapy. Current neoantigen predictors focus on estimation of MHC binding aff...

Performance of a deep learning algorithm for the evaluation of CAD-RADS classification with CCTA.

Atherosclerosis
BACKGROUND AND AIMS: Artificial intelligence (AI) is increasing its role in diagnosis of patients with suspicious coronary artery disease. The aim of this manuscript is to develop a deep convolutional neural network (CNN) to classify coronary compute...

Strengths and Opportunities of Network Medicine in Cardiovascular Diseases.

Circulation journal : official journal of the Japanese Circulation Society
Network medicine can advance current medical practice by arising as response to the limitations of a reductionist approach focusing on cardiovascular (CV) diseases as a direct consequence of a single defect. This molecular-bioinformatic approach inte...

Prediction of lower-grade glioma molecular subtypes using deep learning.

Journal of neuro-oncology
INTRODUCTION: It is useful to know the molecular subtype of lower-grade gliomas (LGG) when deciding on a treatment strategy. This study aims to diagnose this preoperatively.