AIMC Topic: Prospective Studies

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DeepSeeNet: A Deep Learning Model for Automated Classification of Patient-based Age-related Macular Degeneration Severity from Color Fundus Photographs.

Ophthalmology Nov 22, 2018
PURPOSE: In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming partic...
Humans Aged, 80 and over Sensitivity and Specificity Male Middle Aged Disease Progression Severity of Illness Index Prospective Studies Female Reproducibility of Results Risk Factors Aged Photography Retinal Drusen Geographic Atrophy Diagnosis, Computer-Assisted Deep Learning Models, Theoretical Area Under Curve Diagnostic Techniques, Ophthalmological
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Higher serum levels of fibroblast growth factor 21 in old patients with cachexia.

Nutrition (Burbank, Los Angeles County, Calif.) Nov 22, 2018
OBJECTIVE: Fibroblast growth factor (FGF)21 is promptly induced by short fasting in animal models to regulate glucose and fat metabolism. Data on FGF21 in humans are inconsistent and FGF21 has not yet been investigated in old patients with cachexia, ...
Weight Loss Gelatinases Humans Membrane Proteins Serine Endopeptidases Prospective Studies Aged Fibroblast Growth Factors Female Aged, 80 and over Endopeptidases Cross-Sectional Studies Cachexia Male Pilot Projects
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Machine learning in critical care: state-of-the-art and a sepsis case study.

Biomedical engineering online Nov 20, 2018
BACKGROUND: Like other scientific fields, such as cosmology, high-energy physics, or even the life sciences, medicine and healthcare face the challenge of an extremely quick transformation into data-driven sciences. This challenge entails the dauntin...
Expert Systems Medical Informatics Computer Graphics Machine Learning Software Data Analysis Prospective Studies Prognosis Intensive Care Units Reproducibility of Results Sepsis Probability Critical Care Humans Artificial Intelligence
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Ultrasound-Guided Continuous Thoracic Erector Spinae Plane Block Within an Enhanced Recovery Program Is Associated with Decreased Opioid Consumption and Improved Patient Postoperative Rehabilitation After Open Cardiac Surgery-A Patient-Matched, Controlled Before-and-After Study.

Journal of cardiothoracic and vascular anesthesia Nov 19, 2018
OBJECTIVES: Open cardiac surgery may cause severe postoperative pain. The authors hypothesized that patients receiving a bundle of care using continuous erector spinae plane blocks (ESPB) would have decreased perioperative opioid consumption and impr...
Humans Prospective Studies Dose-Response Relationship, Drug Postoperative Care Pain, Postoperative Analgesics, Opioid Female Cardiac Surgical Procedures Middle Aged Thoracic Nerves Pain Management Aged Adolescent Drug Administration Schedule Young Adult Ultrasonography Enhanced Recovery After Surgery Adult Nerve Block Male Follow-Up Studies
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Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients.

Lung cancer (Amsterdam, Netherlands) Nov 19, 2018
OBJECTIVES: A malignant pleural effusion (MPE) is a common complication in non-small cell lung cancer (NSCLC) with important staging and prognostic information. Patients with MPEs are often candidates for advanced therapies, however, the current gold...
Carcinoma, Non-Small-Cell Lung Immunophenotyping Feasibility Studies Pleural Effusion, Malignant Epithelial Cell Adhesion Molecule Pleural Cavity Male Middle Aged Cohort Studies Prognosis Lung Neoplasms Female B7-H1 Antigen Aged Humans Aged, 80 and over Prospective Studies Adult
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Radiomic versus Convolutional Neural Networks Analysis for Classification of Contrast-enhancing Lesions at Multiparametric Breast MRI.

Radiology Nov 13, 2018
Purpose To compare the diagnostic performance of radiomic analysis (RA) and a convolutional neural network (CNN) to radiologists for classification of contrast agent-enhancing lesions as benign or malignant at multiparametric breast MRI. Materials an...
Prospective Studies Female Breast Neoplasms Magnetic Resonance Imaging Breast Humans Neural Networks, Computer Image Interpretation, Computer-Assisted
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Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.

Expert review of gastroenterology & hepatology Nov 13, 2018
BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) Stages 3-5 who were treated with 12 weeks of ritonavir-booste...
Humans Prospective Studies Female Hepatitis C, Chronic Renal Dialysis Valine Viral Load Anilides Time Factors Carbamates Aged Lactams, Macrocyclic Antiviral Agents Egypt Young Adult Genotype Macrocyclic Compounds Adult Sulfonamides Renal Insufficiency, Chronic Kidney Ribavirin Male Hepacivirus Sustained Virologic Response Treatment Outcome Middle Aged Proline Glomerular Filtration Rate Drug Therapy, Combination Cyclopropanes Recovery of Function
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Vasopressin antagonist efficacy and safety in volume-overloaded critically ill patients: a new therapeutic alternative.

European journal of hospital pharmacy : science and practice Nov 10, 2018
OBJECTIVES: To assess tolvaptan's efficacy and safety in critical care patients with volume overload.
Diuretics Tolvaptan Middle Aged Humans Treatment Outcome Prospective Studies Water-Electrolyte Imbalance Critical Illness Antidiuretic Hormone Receptor Antagonists Female Diuresis Male
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Machine learning improves prediction of delayed cerebral ischemia in patients with subarachnoid hemorrhage.

Journal of neurointerventional surgery Nov 10, 2018
BACKGROUND AND PURPOSE: Delayed cerebral ischemia (DCI) is a severe complication in patients with aneurysmal subarachnoid hemorrhage. Several associated predictors have been previously identified. However, their predictive value is generally low. We ...
Tomography, X-Ray Computed Sensitivity and Specificity Cohort Studies Predictive Value of Tests Subarachnoid Hemorrhage Brain Ischemia Humans Machine Learning Prospective Studies Prognosis
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Predicting conversion from clinically isolated syndrome to multiple sclerosis-An imaging-based machine learning approach.

NeuroImage. Clinical Nov 5, 2018
Magnetic resonance imaging (MRI) scans play a pivotal role in the evaluation of patients presenting with a clinically isolated syndrome (CIS), as these may depict brain lesions suggestive of an inflammatory cause. We hypothesized that it is possible ...
Magnetic Resonance Imaging Predictive Value of Tests Multiple Sclerosis Demyelinating Diseases Adult Male Middle Aged Disease Progression Cohort Studies Humans Machine Learning Prospective Studies Female
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