AIMC Topic: Prospective Studies

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Investigation of serum neuroserpin levels in pregnant women diagnosed with pre-eclampsia: a prospective case-control study.

BMC pregnancy and childbirth May 10, 2025
OBJECTIVE: Neuroserpin, a serine protease inhibitor, is recognized for its anti-inflammatory and neuroprotective properties. Given the central role of inflammation and neurological involvement in the pathophysiology of preeclampsia, this study aimed ...
ROC Curve Female Pre-Eclampsia Turkey Young Adult Gestational Age Adult Serpins Severity of Illness Index Humans Neuroserpin Case-Control Studies Prospective Studies Neuropeptides Biomarkers Pregnancy
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Maternal and umbilical cord plasma purine concentrations after oral carbohydrate loading prior to elective Cesarean delivery under spinal anesthesia: a randomized controlled trial.

BMC pregnancy and childbirth May 10, 2025
OBJECTIVE: To evaluate the effect of preoperative intake of oral carbohydrates versus standard preoperative fasting prior to elective cesarean delivery on plasma purine levels (hypoxanthine, xanthine, and uric acid) and beta-hydroxybutyrate (β-HB) in...
Fasting Diet, Carbohydrate Loading Elective Surgical Procedures Uric Acid Anesthesia, Spinal Humans Pregnancy Xanthine Prospective Studies Fetal Blood Female Cesarean Section Purines Adult Preoperative Care 3-Hydroxybutyric Acid Hypoxanthine
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Improving lower-extremity artery depiction and diagnostic confidence using dual-energy technique and popliteal artery monitoring in dual-low dose CT angiography.

Scientific reports May 9, 2025
To assess the utility of dual-energy CT scanning (DECTs) with popliteal artery (PA) monitoring in dual low-dose (radiation and contrast) lower-extremity CT angiography (LE-CTA). 135 patients undergoing LE-CTA were prospectively included and divided i...
Aged Humans Signal-To-Noise Ratio Contrast Media Aged, 80 and over Computed Tomography Angiography Lower Extremity Prospective Studies Adult Popliteal Artery Peripheral Arterial Disease Female Male Radiation Dosage Middle Aged
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A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.

Scientific reports May 8, 2025
This study aimed to demonstrate whether plasma galectin-3 could predict the development of postoperative delirium (POD) in patients with acute aortic dissection (AAD). Prospective, observational study. Cardiac surgery intensive care unit. Consecutive...
Aortic Dissection Galectins Postoperative Complications ROC Curve Blood Proteins Galectin 3 Delirium Risk Factors Aged Male Middle Aged Humans Prospective Studies Biomarkers Female
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Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.

Scientific reports May 8, 2025
Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact their postoperative experience. Among female patients undergoing laparoscopic surgery, the incidence...
Gynecologic Surgical Procedures Promethazine Metoclopramide Female Aged Young Adult Adult Middle Aged Adolescent Double-Blind Method Laparoscopy Postoperative Nausea and Vomiting Antiemetics Humans Prospective Studies
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Physiological comparison of noninvasive ventilation and high-flow nasal oxygen on inspiratory efforts and tidal volumes after extubation: a randomized crossover trial.

Critical care (London, England) May 8, 2025
BACKGROUND: Extubation failure leading to reintubation is associated with high mortality. In patients at high-risk of extubation failure, clinical practice guidelines recommend prophylactic non-invasive ventilation (NIV) over high-flow nasal oxygen (...
Tidal Volume Cross-Over Studies Airway Extubation Oxygen Inhalation Therapy Noninvasive Ventilation Ventilator Weaning Prospective Studies Female Aged Aged, 80 and over Male Humans
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Interpretable machine learning model for predicting post-hepatectomy liver failure in hepatocellular carcinoma.

Scientific reports May 3, 2025
Post-hepatectomy liver failure (PHLF) is a severe complication following liver surgery. We aimed to develop a novel, interpretable machine learning (ML) model to predict PHLF. We enrolled 312 hepatocellular carcinoma (HCC) patients who underwent hepa...
Female Aged Adult Male Middle Aged Humans Machine Learning Algorithms Prospective Studies Hepatectomy Liver Failure Postoperative Complications ROC Curve Liver Neoplasms Carcinoma, Hepatocellular
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Utilizing explainable machine learning for progression-free survival prediction in high-grade serous ovarian cancer: insights from a prospective cohort study.

International journal of surgery (London, England) May 1, 2025
BACKGROUND: High-grade serous ovarian cancer (HGSOC) remains one of the most challenging gynecological malignancies, with over 70% of ovarian cancer patients ultimately experiencing disease progression. The current prognostic tools for progression-fr...
Humans Machine Learning Middle Aged Ovarian Neoplasms Neoplasm Grading Progression-Free Survival Cystadenocarcinoma, Serous Prospective Studies Prognosis Female Aged Adult
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Detection of Pulmonary Nodules on Ultra-low Dose Chest Computed Tomography With Deep-learning Image Reconstruction Algorithm.

Journal of thoracic imaging May 1, 2025
PURPOSE: To evaluate the accuracy of ultra-low dose (ULD) chest computed tomography (CT), with a radiation exposure equivalent to a 2-view chest x-ray, for pulmonary nodule detection using deep learning image reconstruction (DLIR).
Radiographic Image Interpretation, Computer-Assisted Radiation Dosage Radiography, Thoracic Deep Learning Lung Neoplasms Multiple Pulmonary Nodules Solitary Pulmonary Nodule Tomography, X-Ray Computed Female Aged Humans Aged, 80 and over Sensitivity and Specificity Algorithms Adult Cross-Sectional Studies Prospective Studies Male Middle Aged Lung
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Using Machine Learning to Predict Cognitive Decline in Older Adults From the Chinese Longitudinal Healthy Longevity Survey: Model Development and Validation Study.

JMIR aging Apr 30, 2025
BACKGROUND: Cognitive impairment, indicative of Alzheimer disease and other forms of dementia, significantly deteriorates the quality of life of older adult populations and imposes considerable burdens on families and health care systems worldwide. T...
Male China Cognitive Dysfunction Longitudinal Studies Humans East Asian People Machine Learning Prospective Studies Biomarkers Female Aged Aged, 80 and over Longevity
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