AI Medical Compendium Topic

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Deep neural networks integrating genomics and histopathological images for predicting stages and survival time-to-event in colon cancer.

PloS one
MOTIVATION: There exists an unexplained diverse variation within the predefined colon cancer stages using only features from either genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about imp...

Prostate cancer treatment recommendation study based on machine learning and SHAP interpreter.

Cancer science
This study utilized data from 140,294 prostate cancer cases from the Surveillance, Epidemiology, and End Results (SEER) database. Here, 10 different machine learning algorithms were applied to develop treatment options for predicting patients with pr...

Enhancing Missense Variant Pathogenicity Prediction with MissenseNet: Integrating Structural Insights and ShuffleNet-Based Deep Learning Techniques.

Biomolecules
The classification of missense variant pathogenicity continues to pose significant challenges in human genetics, necessitating precise predictions of functional impacts for effective disease diagnosis and personalized treatment strategies. Traditiona...

Individualized prediction of non-sentinel lymph node metastasis in Chinese breast cancer patients with ≥ 3 positive sentinel lymph nodes based on machine-learning algorithms.

BMC cancer
BACKGROUND: Axillary lymph node dissection (ALND) is a standard procedure for early-stage breast cancer (BC) patients with three or more positive sentinel lymph nodes (SLNs). However, ALND can lead to significant postoperative complications without a...

Learning co-plane attention across MRI sequences for diagnosing twelve types of knee abnormalities.

Nature communications
Multi-sequence magnetic resonance imaging is crucial in accurately identifying knee abnormalities but requires substantial expertise from radiologists to interpret. Here, we introduce a deep learning model incorporating co-plane attention across imag...

Predicting Response to Neuromodulators or Prokinetics in Patients With Suspected Gastroparesis Using Machine Learning: The "BMI, Infectious Prodrome, Delayed GES, and No Diabetes" Model.

Clinical and translational gastroenterology
INTRODUCTION: Pharmacologic therapies for symptoms of gastroparesis (GP) have limited efficacy, and it is difficult to predict which patients will respond. In this study, we implemented a machine learning model to predict the response to prokinetics ...

Uncovering early predictors of cerebral palsy through the application of machine learning: a case-control study.

BMJ paediatrics open
OBJECTIVE: Cerebral palsy (CP) is a group of neurological disorders with profound implications for children's development. The identification of perinatal risk factors for CP may lead to improved preventive and therapeutic strategies. This study aime...

Enhancing the Diagnostic Accuracy of Sacroiliitis: A Machine Learning Approach Applied to Computed Tomography Imaging.

British journal of hospital medicine (London, England : 2005)
Sacroiliitis is a challenging condition to diagnose accurately due to the subtle nature of its presentation in imaging studies. This study aims to improve the diagnostic accuracy of sacroiliitis by applying advanced machine learning techniques to co...

SAD: semi-supervised automatic detection of BOLD activations in high temporal resolution fMRI data.

Magma (New York, N.Y.)
OBJECTIVE: Despite the prevalent use of the general linear model (GLM) in fMRI data analysis, assuming a pre-defined hemodynamic response function (HRF) for all voxels can lead to reduced reliability and may distort the inferences derived from it. To...