AIMC Topic: Severity of Illness Index

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Flexion synergy overshadows flexor spasticity during reaching in chronic moderate to severe hemiparetic stroke.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Pharmaceutical intervention targets arm flexor spasticity with an often-unsuccessful goal of improving function. Flexion synergy is a related motor impairment that may be inadvertently neglected. Here, flexor spasticity and flexion synergy...

Prediction of the severity of obstructive sleep apnea by anthropometric features via support vector machine.

PloS one
To develop an applicable prediction for obstructive sleep apnea (OSA) is still a challenge in clinical practice. We apply a modern machine learning method, the support vector machine to establish a predicting model for the severity of OSA. The suppor...

Inter-labeler and intra-labeler variability of condition severity classification models using active and passive learning methods.

Artificial intelligence in medicine
BACKGROUND AND OBJECTIVES: Labeling instances by domain experts for classification is often time consuming and expensive. To reduce such labeling efforts, we had proposed the application of active learning (AL) methods, introduced our CAESAR-ALE fram...

Feasibility of spirography features for objective assessment of motor function in Parkinson's disease.

Artificial intelligence in medicine
OBJECTIVE: Parkinson's disease (PD) is currently incurable, however proper treatment can ease the symptoms and significantly improve the quality of life of patients. Since PD is a chronic disease, its efficient monitoring and management is very impor...

Aging, frailty and complex networks.

Biogerontology
When people age their mortality rate increases exponentially, following Gompertz's law. Even so, individuals do not die from old age. Instead, they accumulate age-related illnesses and conditions and so become increasingly vulnerable to death from va...

Prognosticating Functional Outcome After Intracerebral Hemorrhage: The ICHOP Score.

World neurosurgery
BACKGROUND: The morbidity, mortality, and monetary cost associated with intracerebral hemorrhage (ICH) is devastatingly high. Several scoring systems have been proposed to prognosticate outcomes after ICH, although the original ICH Score is still the...

Sensory tractography and robot-quantified proprioception in hemiparetic children with perinatal stroke.

Human brain mapping
Perinatal stroke causes most hemiparetic cerebral palsy, resulting in lifelong disability. We have demonstrated the ability of robots to quantify sensory dysfunction in hemiparetic children but the relationship between such deficits and sensory tract...

Optimizing Neuropsychological Assessments for Cognitive, Behavioral, and Functional Impairment Classification: A Machine Learning Study.

Behavioural neurology
Subjects with Alzheimer's disease (AD) show loss of cognitive functions and change in behavioral and functional state affecting the quality of their daily life and that of their families and caregivers. A neuropsychological assessment plays a crucial...