BACKGROUND: Obtaining total knee arthroplasty patient-reported outcomes for quality assessment is costly and difficult. We asked whether a large language model (LLM) could interpret electronic health record notes to differentiate patients attaining a...
Pharmacogenetics is a promising strategy to facilitate individualized care for patients with Major Depressive Disorder (MDD). Research is ongoing to identify the optimal genetic markers for predicting outcomes to antidepressant therapies. The primary...
PURPOSE: Age-related macular degeneration (AMD) remains the leading cause of blindness in developed countries. There are many different intravitreal anti-vascular endothelial growth factor (VEGF) drugs available for the treatment of neovascular AMD (...
OBJECTIVE: Software engineering innovations have led to the development of virtual surgical planning software (VSPS) for deformity correction. VSPS uses calibrated radiographs and machine learning predictive models to simulate postoperative spinopelv...
Cardiovascular revascularization medicine : including molecular interventions
Jun 1, 2025
The Cardiovascular Research Technologies (CRT) 2025 conference, a prominent gathering in the field of cardiology, convened more than three thousand attendees from around the world. CRT provides a forum for exemplary education for interventional cardi...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to achieve a pathological complete response (pCR). This study utilizes multi-center cohorts of 2322 pa...
CPT: pharmacometrics & systems pharmacology
Jun 1, 2025
Selective serotonin reuptake inhibitors (SSRIs) are widely used in depression treatment. However, the relationship between treatment efficacy and plasma concentrations remains unclear. We assessed whether the anti-depressive response can be predicted...
Non-specific response to treatment (NSRT) is the primary contributor to the failure of randomized clinical trials in major depressive disorder (MDD). The objective of this study is to develop artificial neural network (ANN) models to predict the indi...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Jun 1, 2025
OBJECTIVES: Directly measuring the causal effect of mechanical thrombectomy (MT) for each ischemic stroke patient remains challenging, as it is impossible to observe the outcomes for both with and without successful recanalization in the same individ...
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