AIMC Topic: Administration, Inhalation

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Exchanging expertise and constructing boundaries: The development of a transnational knowledge network around heroin-assisted treatment.

The International journal on drug policy
Over the last 20 years, supervised injectable and inhalable heroin prescribing has been developed, tested and in some cases introduced as a second line treatment for limited groups of entrenched heroin users in a number of European countries and Cana...

Efficacy and safety of inhaled N-acetylcysteine in idiopathic pulmonary fibrosis: A prospective, single-arm study.

Respiratory investigation
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with few treatment options. The efficacy of N-acetylcysteine in patients with IPF remains controversial. The aim of this research was to investigate the efficacy of inhaled...

Exploring nanoparticles in lungs under COPD conditions for nanospray drug flow and deposition: CFD simulations and AI predictions.

International journal of pharmaceutics
Chronic obstructive pulmonary disease (COPD) plays a heavy burden on individuals and the social health system, not only causing direct medical costs but also economic losses. Today, treatments for COPD include drugs, bronchodilators, and oxygen thera...

Predictive machine learning algorithm for COPD exacerbations using a digital inhaler with integrated sensors.

BMJ open respiratory research
PURPOSE: By using data obtained with digital inhalers, machine learning models have the potential to detect early signs of deterioration and predict impending exacerbations of chronic obstructive pulmonary disease (COPD) for individual patients. This...

Towards Personalized Inhalation Therapy by Correlating Chest CT Imaging and Pulmonary Function Test Features Using Machine Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Inhalation therapy is the predominant method of treatment for a variety of respiratory diseases. The effectiveness of such treatment is dependent on the accuracy of medication delivery. Thus, personalized inhalation therapy wherein inhaler designs ar...

Analysis of the advantages and disadvantages in application of oxygen-driven aerosol and aerosol inhalation by air compressor for the pediatric asthma.

Pakistan journal of pharmaceutical sciences
Present study is done to analyze the advantages and disadvantages in application of oxygen-driven aerosol and aerosol inhalation by air compressor for the pediatric asthma. A total of 180 patients with pediatric bronchial asthma were randomized into ...

A Fresh Shine onCystic Fibrosis Inhalation Therapy: Antimicrobial Synergy of Polymyxin B in Combination with Silver Nanoparticles.

Journal of biomedical nanotechnology
This in vitro study aimed to investigate the synergistic antibacterial activity of polymyxin B in combination with 2 nm silver nanoparticles (NPs) against Gram-negative pathogens commonly isolated from the cystic fibrosis (CF) lung. The in vitro syne...