AIMC Topic: Adult

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Evaluating prediction of short-term tolerability of five type 2 diabetes drug classes using routine clinical features: UK population-based study.

Diabetes, obesity & metabolism
AIMS: A precision medicine approach in type 2 diabetes (T2D) needs to consider potential treatment risks alongside established benefits for glycaemic and cardiometabolic outcomes. Considering five major T2D drug classes, we aimed to describe variatio...

Development and Validation of Ultrasound Hemodynamic-based Prediction Models for Acute Kidney Injury After Renal Transplantation.

Academic radiology
RATIONALE AND OBJECTIVES: Acute kidney injury (AKI) post-renal transplantation often has a poor prognosis. This study aimed to identify patients with elevated risks of AKI after kidney transplantation.

Blood immuno-metabolic biomarker signatures of depression and affective symptoms in young adults.

Brain, behavior, and immunity
BACKGROUND: Depression is associated with alterations in immuno-metabolic biomarkers, but it remains unclear whether these alterations are limited to specific markers, and whether there are subtypes of depression and depressive symptoms which are ass...

Automatic deep learning segmentation of mandibular periodontal bone topography on cone-beam computed tomography images.

Journal of dentistry
OBJECTIVES: This study evaluated the performance of a multi-stage Segmentation Residual Network (SegResNet)-based deep learning (DL) model for the automatic segmentation of cone-beam computed tomography (CBCT) images of patients with stage III and IV...

RIPTOSO: The development of a screening tool for adverse events during forensic-psychiatric inpatient treatments of offenders with schizophrenia spectrum disorders.

Psychiatry research
Adverse events such as compulsory measures, absconding, illicit substance use, self-harm, aggressive behavior, and prolonged hospitalization pose significant challenges in forensic psychiatric inpatient care. This study introduces a machine learning-...

Detection of Early-Stage Colorectal Cancer Using Cell-Free oncRNA Biomarkers and Artificial Intelligence.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Colorectal cancer is the second leading cause of cancer-related deaths worldwide, and early detection significantly improves treatment outcomes, but existing blood-based tests often have limited sensitivity in early-stage disease. We develop...

Breast cancer neoadjuvant therapy outcome prediction based on clinical patient and tumor features: A cross-sectional study.

Current problems in cancer
INTRODUCTION: Breast cancer is the most common malignant disease in the female population and one of the most common diseases in developed countries. Many factors which may impact the development and outcome of this complex disease have been investig...

Development of patient-specific apparent blood viscosity predictive models for computational fluid dynamics analysis of intracranial aneurysms with machine learning approaches.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: A model to predict patient-specific apparent viscosity as a computational condition in computational fluid dynamics (CFD) analysis, which is used in research on intracranial aneurysms, is important. The purpose of this stud...

ChatGPT-4 vs. multi-disciplinary tumor board decisions for the therapeutic management of primary laryngeal cancer.

Acta oto-laryngologica
BACKGROUND: Artificial intelligence-based clinical decision support systems are promising tools for addressing the increasing complexity of oncological data and treatment. However, the integration and validation of models such as ChatGPT within multi...

Neural Network-based Automated Classification of 18 F-FDG PET/CT Lesions and Prognosis Prediction in Nasopharyngeal Carcinoma Without Distant Metastasis.

Clinical nuclear medicine
PURPOSE: To evaluate the diagnostic performance of the PET Assisted Reporting System (PARS) in nasopharyngeal carcinoma (NPC) patients without distant metastasis, and to investigate the prognostic significance of the metabolic parameters.