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Age of Onset

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Complete Molar Pregnancy in Posmenopausal Woman-a Case Report.

Medical archives (Sarajevo, Bosnia and Herzegovina)
INTRODUCTION: Gestational trophoblastic desease (GTD) is disease typical for reproductive period of women and is extremly rare in postmenopausal period of woman's life.

Impact of age at onset on the phenomenology of depression in treatment-seeking adults in the STAR*D trial.

Journal of affective disorders
BACKGROUND: - Adolescence is characterized by biological, emotional, and behavioral changes. The onset of depression during this vulnerable time may confer specific risks. This study examined whether symptoms of depression were associated with age at...

Machine-learning-derived rules set excludes risk of Parkinson's disease in patients with olfactory or gustatory symptoms with high accuracy.

Journal of neurology
BACKGROUND: Chemosensory loss is a symptom of Parkinson's disease starting already at preclinical stages. Their appearance without an identifiable etiology therefore indicates a possible early symptom of Parkinson's disease. Supervised machine-learni...

Identification of prognostic factors for pediatric myocarditis with a random forests algorithm-assisted approach.

Pediatric research
BACKGROUND: Pediatric myocarditis is a rare disease with substantial mortality. Little is known regarding its prognostic factors. We hypothesize that certain comorbidities and procedural needs may increase risks of poor outcomes. This study aims to i...

Data-driven approaches to advance research and clinical care for pediatric cancer.

Biochimica et biophysica acta. Reviews on cancer
Pediatric cancer is a rare disease with a distinct etiology and mutational landscape compared with adult cancer. Multi-omics profiling of retrospective and prospective cohorts coupled with innovative computational analysis have been instrumental in u...

Development and validation of a new diabetes index for the risk classification of present and new-onset diabetes: multicohort study.

Scientific reports
In this study, we aimed to propose a novel diabetes index for the risk classification based on machine learning techniques with a high accuracy for diabetes mellitus. Upon analyzing their demographic and biochemical data, we classified the 2013-16 Ko...

Paediatric/young versus adult patients with long QT syndrome.

Open heart
INTRODUCTION: Long QT syndrome (LQTS) is a less prevalent cardiac ion channelopathy than Brugada syndrome in Asia. The present study compared the outcomes between paediatric/young and adult LQTS patients.