AIMC Topic: Aged

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Options for postoperative radiation therapy in patients with de novo metastatic breast cancer.

Breast (Edinburgh, Scotland)
BACKGROUND: Although meta-analyses have demonstrated survival benefits associated with primary tumor resection in MBC, guidelines lack consensus on the survival benefit of postoperative radiation therapy (RT).

IDENTIFYING A SEPSIS SUBPHENOTYPE CHARACTERIZED BY DYSREGULATED LIPOPROTEIN METABOLISM USING A SIMPLIFIED CLINICAL DATA ALGORITHM.

Shock (Augusta, Ga.)
Background: Cholesterol metabolism is dysregulated in sepsis contributing to patient heterogeneity. Subphenotypes displaying lower lipoprotein levels and higher mortality (previously subphenotyped hypolipoprotein phenotype [HYPO]) or higher lipoprote...

Impact of CT reconstruction algorithms on pericoronary and epicardial adipose tissue attenuation.

European journal of radiology
OBJECTIVE: This study aims to investigate the impact of adaptive statistical iterative reconstruction-Veo (ASIR-V) and deep learning image reconstruction (DLIR) algorithms on the quantification of pericoronary adipose tissue (PCAT) and epicardial adi...

Predictive Analysis of Amyotrophic Lateral Sclerosis Progression and Mortality in a Clinic Cohort From Singapore.

Muscle & nerve
INTRODUCTION: There is currently no comprehensive Amyotrophic Lateral Sclerosis (ALS) patient database in Singapore comparable to those available in Europe and the United States. We established the Singapore ALS registry (SingALS) to draw meaningful ...

Feasibility of human ethomic biomarkers for the diagnosis and monitoring of hip osteoarthritis.

Journal of biomechanics
Radiographic imaging is typically used to diagnose osteoarthritis (OA). However, patients would typically be sent for imaging after they present to a physician because of joint pain. By this time, the condition is likely irreversible. This study aims...

Deep learning-based post hoc denoising for 3D volume-rendered cardiac CT in mitral valve prolapse.

The international journal of cardiovascular imaging
We hypothesized that deep learning-based post hoc denoising could improve the quality of cardiac CT for the 3D volume-rendered (VR) imaging of mitral valve (MV) prolapse. We aimed to evaluate the quality of denoised 3D VR images for visualizing MV pr...

The predictive role of identifying frailty in assessing the need for palliative care in the elderly: the application of machine learning algorithm.

Journal of health, population, and nutrition
BACKGROUND: Palliative care is a key component of integrated care to improve care quality and reduce hospitalization costs for patients with chronic obstructive pulmonary disease (COPD). This study aims to use machine learning algorithms to create an...

Interpretable machine learning model for predicting delirium in patients with sepsis: a study based on the MIMIC data.

BMC infectious diseases
OBJECTIVE: The aim of this study was to construct interpretable machine learning models to predict the risk of developing delirium in patients with sepsis and to explore the impact of delirium on the 28-day survival rate of patients.