AIMC Topic: Aged

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Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing.

BMC infectious diseases
BACKGROUND: Remdesivir (RDV) was the first antiviral approved for mild-to-moderate COVID-19 and for those patients at risk for progression to severe disease after clinical trials supported its association with improved outcomes. Real-world evidence (...

Automated phenotyping of mild cognitive impairment and Alzheimer's disease and related dementias using electronic health records.

International journal of medical informatics
OBJECTIVES: Unstructured and structured data in electronic health records (EHR) are a rich source of information for research and quality improvement studies. However, extracting accurate information from EHR is labor-intensive. Timely and accurate i...

A High-resolution T2WI-based Deep Learning Model for Preoperative Discrimination Between T2 and T3 Rectal Cancer: A Multicenter Study.

Academic radiology
RATIONALE AND OBJECTIVES: To construct a deep learning model (DL) based on high-resolution T2-weighted images for preoperative differentiation between T2 and T3 stage rectal cancer (RC), and to compare its performance with experienced radiologists.

Dietary and lifestyle determinants of vitamin D status in the UK Biobank Cohort study for predictive modeling.

The Journal of nutritional biochemistry
Vitamin D (VD) is involved in a wide variety of physiological processes. The high prevalence of VD deficiency in the population requires stronger preventive measures. The aim was to characterize the dietary and lifestyle determinants of VD levels in ...

Deep learning-based prediction of enhanced CT scans for lymph node metastasis in esophageal squamous cell carcinoma.

Japanese journal of radiology
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) poses a significant global health challenge with a particularly grim prognosis. Accurate prediction of lymph node metastasis (LNM) in ESCC is crucial for optimizing treatment strategies and improv...

A comparison of an integrated and image-only deep learning model for predicting the disappearance of indeterminate pulmonary nodules.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
BACKGROUND: Indeterminate pulmonary nodules (IPNs) require follow-up CT to assess potential growth; however, benign nodules may disappear. Accurately predicting whether IPNs will resolve is a challenge for radiologists. Therefore, we aim to utilize d...

External Validation of an Artificial Intelligence Algorithm Using Biparametric MRI and Its Simulated Integration with Conventional PI-RADS for Prostate Cancer Detection.

Academic radiology
PURPOSE: Prostate imaging reporting and data systems (PI-RADS) experiences considerable variability in inter-reader performance. Artificial Intelligence (AI) algorithms were suggested to provide comparable performance to PI-RADS for assessing prostat...

IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images.

NeuroImage
Alzheimer's disease (AD) represents a significant challenge due to its progressive neurodegenerative impact, particularly within an aging global demographic. This underscores the critical need for developing sophisticated diagnostic tools for its ear...