AIMC Topic: Aged

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Deep Geometric Learning With Monotonicity Constraints for Alzheimer's Disease Progression.

IEEE transactions on neural networks and learning systems
Alzheimer's disease (AD) is a devastating neurodegenerative condition that precedes progressive and irreversible dementia; thus, predicting its progression over time is vital for clinical diagnosis and treatment. For this, numerous studies have imple...

Machine learning based association between inflammation indicators (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality in arthritis patients with hypertension: NHANES 1999-2018.

Frontiers in public health
BACKGROUND: This study aimed to evaluate the relationship between CBC-derived inflammatory markers (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality (ACM) risk in arthritis (AR) patients with hypertensive (HTN) using data from the NHANES.

Direct-acting antivirals (DAA) positively affect depression and cognitive function in patients with chronic hepatitis C.

PloS one
The aim of the study was to determine how depression and cognitive dysfunction in patients with chronic hepatitis C virus (HCV) infection are affected by treatment with direct-acting antivirals (DAA). Fifty-two chronic hepatitis C patients underwent ...

An interpretable radiomics-based machine learning model for predicting reverse left ventricular remodeling in STEMI patients using late gadolinium enhancement of myocardial scar.

European radiology
OBJECTIVES: To evaluate the added value of the late gadolinium enhancement (LGE)-scar radiomics features in predicting reverse left ventricular remodeling (r-LVR) in ST-segment elevation myocardial infarction (STEMI) patients using machine learning (...

Arterial phase CT radiomics for non-invasive prediction of Ki-67 proliferation index in pancreatic solid pseudopapillary neoplasms.

Abdominal radiology (New York)
BACKGROUND: This study aimed to preoperatively predict Ki-67 proliferation levels in patients with pancreatic solid pseudopapillary neoplasm (pSPN) using radiomics features extracted from arterial phase helical CT images.

Artificial Intelligence Model for Time Series Classification: Prediction of Delayed Balloon Expulsion Test Using High-Resolution Anorectal Manometry Data and Time-Series Integrated Pressurized Volume.

Neurogastroenterology and motility
BACKGROUND: We previously demonstrated the novel concept of using the integrated pressurized volume (IPV) with high-resolution anorectal manometry (HRAM) and found that it was predictive of delayed balloon expulsion (BE) test results. However, previo...

Estimating depression severity in narrative clinical notes using large language models.

Journal of affective disorders
BACKGROUND: Depression treatment guidelines emphasize measurement-based care using patient-reported outcome measures, yet their impact on narrative documentation quality remains underexplored.

5-5-5 ABRT (Dose of 5 Gy per Fraction for up to 5 Fractions Over 5 Weeks Adaptive Bridging Radiation Therapy)-Artificial Intelligence Enters the CAR (-T) (Chimeric Antigen Receptor-T) in Relapsed/Refractory Large B Cell Lymphoma.

International journal of radiation oncology, biology, physics
PURPOSE: Bridging radiation therapy (BRT) is effective for local control in patients with relapsed or refractory large B cell lymphoma who are undergoing chimeric antigen receptor (CAR) T cell therapy. We hypothesized that adaptive BRT (ABRT), which ...

Effects of Renal Function on the Multimodal Brain Networks Affecting Mild Cognitive Impairment Converters in End-Stage Renal Disease.

Academic radiology
RATIONALE AND OBJECTIVES: Cognitive decline is common in End-Stage Renal Disease (ESRD) patients, yet its neural mechanisms are poorly understood. This study investigates structural and functional brain network reconfiguration in ESRD patients transi...

A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.

The Journal of pathology
Microsatellite instability is a strong predictor of response to immune checkpoint therapy and patient outcome in colorectal cancer. Although enrichment of distinct T-cell subpopulations has been determined to impact the response to immune checkpoint ...