AIMC Topic: Alkaloids

Clear Filters Showing 11 to 20 of 22 articles

A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.

Nutrients Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Disease Models, Animal Metabolic Syndrome Dietary Supplements Liver Diet, High-Fat Lipids Coffea Non-alcoholic Fatty Liver Disease Time Factors Insulin Resistance Seeds Rats, Sprague-Dawley Animals Blood Glucose Insulin Dietary Sucrose Alkaloids Cytokines Diterpenes Caffeic Acids Carbon-13 Magnetic Resonance Spectroscopy
View on PubMed DOI

Antimicrobial Furoquinoline Alkaloids from Vepris lecomteana (Pierre) Cheek & T. Heller (Rutaceae).

Molecules (Basel, Switzerland) Dec 21, 2017
Three new prenylated furoquinoline alkaloids named lecomtequinoline A (), B (), and C (), together with the known compounds anhydroevoxine (), evoxine (), dictamnine (), methylflindersine (), evoxanthine (), hesperidin, lupeol, -sitosterol, stigmaste...
Quinolines Micrococcus luteus Staphylococcaceae Plant Extracts Escherichia coli Rutaceae Humans Bacillus subtilis Molecular Structure Anti-Bacterial Agents Plant Leaves Plant Stems Microbial Sensitivity Tests Alkaloids
View on PubMed DOI

Desert actinobacteria as a source of bioactive compounds production with a special emphases on Pyridine-2,5-diacetamide a new pyridine alkaloid produced by Streptomyces sp. DA3-7.

Microbiological research Nov 21, 2017
In the present study, 134 morphologically distinct actinobacteria isolates were obtained from soil samples from 10 different localities in the Saudi Arabian desert. The preliminary screening revealed that 16 of these isolates possessed antimicrobial ...
Cell Line, Tumor Humans Adenocarcinoma Anti-Infective Agents Escherichia coli Enterococcus faecalis Breast Neoplasms Female Soil Microbiology Streptomyces Alkaloids Antineoplastic Agents Desert Climate Cryptococcus neoformans Salmonella typhimurium Saudi Arabia Pyridines Microbial Sensitivity Tests MCF-7 Cells
View on PubMed DOI

Anticancer and anti-inflammatory activities of girinimbine isolated from .

Drug design, development and therapy Dec 28, 2016
Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a...
Cell Proliferation Apoptosis Lipopolysaccharides Dose-Response Relationship, Drug Cytokines Animals Mice Nitric Oxide Anti-Inflammatory Agents, Non-Steroidal Zebrafish Alkaloids HT29 Cells Cell Survival Antineoplastic Agents, Phytogenic Drug Screening Assays, Antitumor Structure-Activity Relationship Humans Tumor Cells, Cultured Murraya
View on PubMed DOI

Parts-per-trillion detection of harmala alkaloids in Undaria pinnatifida algae by on-line solid phase extraction capillary electrophoresis mass spectrometry.

Analytica chimica acta Dec 26, 2016
β-carboline alkaloids of the harmala group (HAlks)-a family of compounds with pharmacologic effects-can be found at trace levels (<25 μg kg algae) in the edible invasive algae Undaria pinnatifida, known commonly as wakame. In this study, we present a...
Solid Phase Extraction Mass Spectrometry Electrophoresis, Capillary Alkaloids Undaria
View on PubMed DOI

ANTIOXIDANT ACTIVITY AND FT-IR ANALYSIS OF AND LEAF AND SEED METHANOLIC EXTRACTS.

African journal of traditional, complementary, and alternative medicines : AJTCAM Aug 12, 2016
BACKGROUND: (family- Solanaceae), has a long history of being used as herbal medicine. These medicinal effects have been attributed to the phytochemicals present in the plant leaves and seeds, in particular alkaloids, flavonoids and phenolic compoun...
Plant Leaves Flavonoids Phenols Methanol Lipid Peroxidation Alkaloids Datura Antioxidants Plant Extracts Spectroscopy, Fourier Transform Infrared Seeds
View on PubMed DOI

Envisaging the Regulation of Alkaloid Biosynthesis and Associated Growth Kinetics in Hairy Roots of Vinca minor Through the Function of Artificial Neural Network.

Applied biochemistry and biotechnology Dec 3, 2015
Artificial neural network based modeling is a generic approach to understand and correlate different complex parameters of biological systems for improving the desired output. In addition, some new inferences can also be predicted in a shorter time w...
Vinca Neural Networks, Computer Plant Roots Alkaloids
View on PubMed DOI

Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Corydalis bungeana Turcz extract.

Journal of separation science Nov 26, 2015
Pharmacokinetic studies were conducted on rats for protopine, corynoline, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)-ethyl]propenamide, acetylcorynoline, and 8-oxocorynoline, five main active components from Corydalis bungeana Turcz (C. bungeana...
Corydalis Animals Male Drugs, Chinese Herbal Rats Chromatography, High Pressure Liquid Rats, Sprague-Dawley Tandem Mass Spectrometry Alkaloids
View on PubMed DOI

Machine Learning Algorithms Identify Target Genes and the Molecular Mechanism of Matrine against Diffuse Large B-cell Lymphoma.

Current computer-aided drug design Jan 1, 2024
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma worldwide. Novel treatment strategies are still needed for this disease.
Humans Machine Learning Algorithms Signal Transduction Alkaloids Quinolizines Lymphoma, Large B-Cell, Diffuse Matrines Molecular Docking Simulation Gene Regulatory Networks Gene Expression Regulation, Neoplastic
View on PubMed DOI

Alkaloids, flavonoids, polyphenols might be responsible for potent antiarthritic effect of Solanum nigrum.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Oct 1, 2019
OBJECTIVE: To evaluate in vitro and in vivo antiarthritic potential of Solanum nigrum (S. nigrum).
Flavonoids Arthritis, Rheumatoid Female Alkaloids Rats Animals Antirheumatic Agents Rats, Sprague-Dawley Male Solanum nigrum Polyphenols
View on PubMed
Popular Topics
Recent Journals