AIMC Topic: Apoptosis

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Anticancer and anti-inflammatory activities of girinimbine isolated from .

Drug design, development and therapy Dec 28, 2016
Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a...
Anti-Inflammatory Agents, Non-Steroidal Zebrafish Alkaloids HT29 Cells Cell Survival Antineoplastic Agents, Phytogenic Drug Screening Assays, Antitumor Structure-Activity Relationship Tumor Cells, Cultured Murraya Cytokines Animals Mice Nitric Oxide Cell Proliferation Apoptosis Lipopolysaccharides Dose-Response Relationship, Drug Humans
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The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice.

European journal of histochemistry : EJH Dec 28, 2016
Diarrhoea is a common cause of death in children and weaned animals. Recent research has found that serotonin (5-HT) in the gastrointestinal tract plays an important role in regulating growth and the maintenance of mucosa, which protect against diarr...
Diarrhea Mice Disease Models, Animal Apoptosis Animals Male Senna Extract Intestinal Mucosa Mice, Inbred ICR Intestine, Small Serotonin
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Large-scale inference of gene function through phylogenetic annotation of Gene Ontology terms: case study of the apoptosis and autophagy cellular processes.

Database : the journal of biological databases and curation Dec 26, 2016
We previously reported a paradigm for large-scale phylogenomic analysis of gene families that takes advantage of the large corpus of experimentally supported Gene Ontology (GO) annotations. This 'GO Phylogenetic Annotation' approach integrates GO ann...
Humans Phylogeny Autophagy Software Models, Genetic Molecular Sequence Annotation Animals Apoptosis Gene Ontology Evolution, Molecular
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Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish.

Materials science & engineering. C, Materials for biological applications Dec 23, 2016
The aim of this study was to evaluate the anticancer activity of bioinspired silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) against mouse myoblast cancer cells (CC). Both AgNPs and AuNPs were biologically synthesized using Spinacia olera...
Caspases Myoblasts Toxicity Tests X-Ray Diffraction Embryo, Nonmammalian Antineoplastic Agents Acridine Orange Photoacoustic Techniques Gold Cell Line, Tumor Plant Extracts Cell Shape Metal Nanoparticles Spinacia oleracea Mice Ethidium Apoptosis Silver Staining and Labeling Cell Survival Zebrafish Animals Plant Leaves
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Pectic Oligosaccharide from tomato exhibiting anticancer potential on a gastric cancer cell line: Structure-function relationship.

Carbohydrate polymers Dec 20, 2016
Pectic Polysaccharide (PP) from dietary sources has been known to prevent cancer growth and hence impede cancer progression. We evaluated anticancer effect of Pectic-Oligosaccharide isolated from Sour Raw Tomato (SrTPO); its bioavailability and struc...
Solanum lycopersicum Oligosaccharides Pectins Cell Line, Tumor Apoptosis Humans Antineoplastic Agents, Phytogenic Stomach Neoplasms Structure-Activity Relationship
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Apoptosis of rat hepatic stellate cells induced by diallyl trisulfide and proteomics profiling in vitro.

Canadian journal of physiology and pharmacology Nov 18, 2016
Diallyl trisulfide (DATS), a major garlic derivative, inhibits cell proliferation and triggers apoptosis in a variety of cancer cell lines. However, the effects of DATS on hepatic stellate cells (HSCs) remain unknown. The aim of this study was to ana...
Hepatic Stellate Cells Sulfides Gene Expression Regulation Allyl Compounds Cell Cycle Garlic Proteomics Cell Proliferation Animals Apoptosis Rats Cell Survival
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Vitamin E (α-Tocopherol) Exhibits Antitumour Activity on Oral Squamous Carcinoma Cells ORL-48.

Integrative cancer therapies Nov 10, 2016
Cancers involving the oral cavity, head, and neck regions are often treated with cisplatin. In cancer therapy, the main target is to eliminate unwanted cancerous cells. However, reports on the nonselective nature of this drug have raised few concerns...
Cisplatin Humans alpha-Tocopherol Carcinoma, Squamous Cell Cell Cycle Checkpoints Antineoplastic Agents Vitamin E Cell Line, Tumor Annexin A5 Oxidative Stress G1 Phase Antioxidants Resting Phase, Cell Cycle Apoptosis
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Detrended cross-correlation coefficient: Application to predict apoptosis protein subcellular localization.

Mathematical biosciences Oct 6, 2016
Apoptosis, or programed cell death, plays a central role in the development and homeostasis of an organism. Obtaining information on subcellular location of apoptosis proteins is very helpful for understanding the apoptosis mechanism. The prediction ...
Support Vector Machine Apoptosis Apoptosis Regulatory Proteins Position-Specific Scoring Matrices Models, Theoretical
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Identification of informative genes and pathways using an improved penalized support vector machine with a weighting scheme.

Computers in biology and medicine Aug 4, 2016
Incorporation of pathway knowledge into microarray analysis has brought better biological interpretation of the analysis outcome. However, most pathway data are manually curated without specific biological context. Non-informative genes could be incl...
Gene Regulatory Networks Mice Computational Biology Support Vector Machine Animals Neoplasms Gene Expression Profiling Transcriptome Humans Apoptosis Microarray Analysis Cell Cycle
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PHYTOCHEMISTRY, CYTOTOXICITY AND APOPTOSIS STUDIES OF B-SITOSTEROL-3--GLUCOSIDE AND Β -AMYRIN FROM .

African journal of traditional, complementary, and alternative medicines : AJTCAM Jul 3, 2016
BACKGROUND: is used traditionally in many countries for the treatment of cancer and benign prostate hyperplasia.
Glucosides Apoptosis Humans Prunus africana Cell Survival HEK293 Cells Plant Extracts Plant Leaves Oleanolic Acid Hep G2 Cells Caco-2 Cells Sitosterols
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