AIMC Topic: Astrocytes

Clear Filters Showing 21 to 30 of 34 articles

A multistep deep learning framework for the automated detection and segmentation of astrocytes in fluorescent images of brain tissue.

Scientific reports Mar 20, 2020
While astrocytes have been traditionally described as passive supportive cells, studies during the last decade have shown they are active players in many aspects of CNS physiology and function both in normal and disease states. However, the precise m...
Brain Deep Learning Image Processing, Computer-Assisted Astrocytes Humans Neural Networks, Computer Algorithms
View on PubMed DOI

Utilizing supervised machine learning to identify microglia and astrocytes in situ: implications for large-scale image analysis and quantification.

Journal of neuroscience methods Sep 5, 2019
BACKGROUND: The evaluation of histological tissue samples plays a crucial role in deciphering preclinical disease and injury mechanisms. High-resolution images can be obtained quickly however data acquisition are often bottlenecked by manual analysis...
Neurosciences Mice Reproducibility of Results Supervised Machine Learning Rats Sensitivity and Specificity Animals, Genetically Modified Microglia Animals Fluorescent Antibody Technique Astrocytes Image Processing, Computer-Assisted Histological Techniques
View on PubMed DOI

Information Transmitted From Bioinspired Neuron-Astrocyte Network Improves Cortical Spiking Network's Pattern Recognition Performance.

IEEE transactions on neural networks and learning systems Apr 11, 2019
We trained two spiking neural networks (SNNs), the cortical spiking network (CSN) and the cortical neuron-astrocyte network (CNAN), using a spike-based unsupervised method, on the MNIST and alpha-digit data sets and achieve an accuracy of 96.1% and 7...
Computer Simulation Action Potentials Astrocytes Neurons Humans Neural Networks, Computer Machine Learning Algorithms Pattern Recognition, Automated Cerebral Cortex Electroencephalography Phase Synchronization Alpha Rhythm
View on PubMed DOI

Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.

Oxidative medicine and cellular longevity Dec 18, 2018
Postcardiac arrest syndrome yields poor neurological outcomes, but the mechanisms underlying this condition remain poorly understood. Autophagy plays an important role in neuronal apoptosis induced by ischemia. However, whether autophagy is involved ...
Mice, Inbred C57BL Oxidative Stress Quinolines Neurons Reperfusion Injury Cells, Cultured Transient Receptor Potential Channels Astrocytes Mice Animals Phthalimides Autophagy Disease Models, Animal Male Ischemic Attack, Transient Apoptosis Microtubule-Associated Proteins
View on PubMed DOI

A deep convolutional neural network approach for astrocyte detection.

Scientific reports Aug 27, 2018
Astrocytes are involved in various brain pathologies including trauma, stroke, neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, or chronic pain. Determining cell density in a complex tissue environment in microscopy images an...
Rats Area Under Curve Astrocytes Models, Biological Machine Learning Software Animals Image Processing, Computer-Assisted Humans Neural Networks, Computer
View on PubMed DOI

Improved Perceptual Learning by Control of Extracellular GABA Concentration by Astrocytic Gap Junctions.

Neural computation Oct 24, 2017
Learning of sensory cues is believed to rely on synchronous pre- and postsynaptic neuronal firing. Evidence is mounting that such synchronicity is not merely caused by properties of the underlying neuronal network but could also depend on the integri...
Perception gamma-Aminobutyric Acid Nerve Net Gap Junctions Membrane Potentials GABA Plasma Membrane Transport Proteins Extracellular Fluid Astrocytes Learning Neurons Animals Nonlinear Dynamics Models, Neurological Neural Networks, Computer
View on PubMed DOI

The Essential Oils of Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities.

Oxidative medicine and cellular longevity Dec 18, 2016
The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the di...
Saccharomyces cerevisiae Leuzea Anti-Inflammatory Agents Tumor Necrosis Factor-alpha Pseudomonas aeruginosa Interleukin-6 Gas Chromatography-Mass Spectrometry Reactive Oxygen Species Microbial Sensitivity Tests Enterococcus faecalis Plant Roots Oils, Volatile Interleukin-1beta Humans Enzyme-Linked Immunosorbent Assay Astrocytes Anti-Infective Agents Candida albicans Lipopolysaccharides Cell Line
View on PubMed DOI

CSF YKL-40 and pTau181 are related to different cerebral morphometric patterns in early AD.

Neurobiology of aging Nov 2, 2015
Cerebrospinal fluid (CSF) concentrations of YKL-40 that serve as biomarker of neuroinflammation are known to be altered along the clinico-biological continuum of Alzheimer's disease (AD). The specific structural cerebral correlates of CSF YKL-40 were...
Female Aged Male Middle Aged Cognitive Dysfunction Inflammation Magnetic Resonance Imaging Astrocytes Humans Biomarkers tau Proteins Amyloid beta-Peptides Chitinase-3-Like Protein 1 Alzheimer Disease Neuroglia Neuroimaging Gray Matter
View on PubMed DOI

On the role of astroglial syncytia in self-repairing spiking neural networks.

IEEE transactions on neural networks and learning systems Jan 6, 2015
It has been shown that brain-like self-repair can arise from the interactions between neurons and astrocytes where endocannabinoids are synthesized and released from active neurons. This retrograde messenger feeds back to local synapses directly and ...
Neural Networks, Computer Models, Neurological Action Potentials Astrocytes Neurons Humans Synapses Nerve Net
View on PubMed DOI

Spiking Neuron-Astrocyte Networks for Image Recognition.

Neural computation Mar 18, 2025
From biological and artificial network perspectives, researchers have started acknowledging astrocytes as computational units mediating neural processes. Here, we propose a novel biologically inspired neuron-astrocyte network model for image recognit...
Action Potentials Astrocytes Neurons Nerve Net Humans Neural Networks, Computer Animals Models, Neurological
View on PubMed DOI
Popular Topics
Recent Journals