AIMC Topic: Diabetes Mellitus, Type 2

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Urinary Complement proteome strongly linked to diabetic kidney disease progression.

Nature communications
Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...

Exhaled gas biomarkers: a non-invasive approach for distinguishing diabetes and its complications.

The Analyst
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...

Association between air pollution and type II diabetes in Italy from clinical data and population-weighted exposure at the municipality level.

Scientific reports
A growing body of literature supports the association between ambient particulate pollution and the risk of type 2 diabetes (T2DM). Both issues are particularly relevant in Italy. This study investigates the relationship between T2DM and exposure to ...

Conditional universal differential equations capture population dynamics and interindividual variation in c-peptide production.

NPJ systems biology and applications
Universal differential equations (UDEs) are an emerging approach in biomedical systems biology, integrating physiology-driven mathematical models with machine learning for data-driven model discovery in areas where knowledge of the underlying physiol...

A multimodal deep learning architecture for predicting interstitial glucose for effective type 2 diabetes management.

Scientific reports
The accurate prediction of blood glucose is critical for the effective management of diabetes. Modern continuous glucose monitoring (CGM) technology enables real-time acquisition of interstitial glucose concentrations, which can be calibrated against...

Transfer learning prediction of type 2 diabetes with unpaired clinical and genetic data.

Scientific reports
The prevalence of type 2 diabetes mellitus (T2DM) in Korea has risen in recent years, yet many cases remain undiagnosed. Advanced artificial intelligence models using multi-modal data have shown promise in disease prediction, but two major challenges...

Machine learning driven diabetes care using predictive-prescriptive analytics for personalized medication prescription.

Scientific reports
The increasing prevalence of type 2 diabetes (T2D) is a significant health concern worldwide. Effective and personalized treatment strategies are essential for improving patient outcomes and reducing healthcare costs. Machine learning (ML) has the po...

AI-Driven segmentation and morphogeometric profiling of epicardial adipose tissue in type 2 diabetes.

Cardiovascular diabetology
BACKGROUND: Epicardial adipose tissue (EAT) is associated with cardiometabolic risk in type 2 diabetes (T2D), but its spatial distribution and structural alterations remain understudied. We aim to develop a shape-aware, AI-based method for automated ...

Predicting postprandial glucose excursions to personalize dietary interventions for type-2 diabetes management.

Scientific reports
Elevated postprandial glucose levels present a global epidemic and a major challenge in type-2 diabetes (T2D) management. A key barrier to developing effective dietary interventions for T2D management is the wide inter-individual variation in glycemi...