AIMC Topic: Disease Progression

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Fused Sparse Network Learning for Longitudinal Analysis of Mild Cognitive Impairment.

IEEE transactions on cybernetics Dec 22, 2020
Alzheimer's disease (AD) is a neurodegenerative disease with an irreversible and progressive process. To understand the brain functions and identify the biomarkers of AD and early stages of the disease [also known as, mild cognitive impairment (MCI)]...
Cognitive Dysfunction Support Vector Machine Magnetic Resonance Imaging Alzheimer Disease Image Interpretation, Computer-Assisted Humans Neural Networks, Computer Brain Disease Progression
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Prediction of disease progression in patients with COVID-19 by artificial intelligence assisted lesion quantification.

Scientific reports Dec 16, 2020
To investigate the value of artificial intelligence (AI) assisted quantification on initial chest CT for prediction of disease progression and clinical outcome in patients with coronavirus disease 2019 (COVID-19). Patients with confirmed COVID-19 inf...
Artificial Intelligence COVID-19 Retrospective Studies Tomography, X-Ray Computed Female Humans ROC Curve Image Processing, Computer-Assisted Area Under Curve Multivariate Analysis Male Middle Aged Disease Progression Lung Severity of Illness Index SARS-CoV-2 Aged Aged, 80 and over Adult
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Transfer learning for predicting conversion from mild cognitive impairment to dementia of Alzheimer's type based on a three-dimensional convolutional neural network.

Neurobiology of aging Dec 13, 2020
Dementia of Alzheimer's type (DAT) is associated with devastating and irreversible cognitive decline. Predicting which patients with mild cognitive impairment (MCI) will progress to DAT is an ongoing challenge in the field. We developed a deep learni...
Disease Progression Deep Learning Cognitive Dysfunction Imaging, Three-Dimensional Logistic Models Brain Female Aged Male Magnetic Resonance Imaging Predictive Value of Tests Alzheimer Disease Neuroimaging Humans Neural Networks, Computer
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End-to-End Deep Learning Model for Predicting Treatment Requirements in Neovascular AMD From Longitudinal Retinal OCT Imaging.

IEEE journal of biomedical and health informatics Dec 4, 2020
Neovascular age-related macular degeneration (nAMD) is nowadays successfully treated with anti-VEGF substances, but inter-individual treatment requirements are vastly heterogeneous and currently poorly plannable resulting in suboptimal treatment freq...
Disease Progression Deep Learning Tomography, Optical Coherence Humans Image Interpretation, Computer-Assisted Retina Algorithms Macular Degeneration
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Prediction of disease progression and outcomes in multiple sclerosis with machine learning.

Scientific reports Dec 3, 2020
Multiple Sclerosis is a chronic inflammatory disease, affecting the Central Nervous System and leading to irreversible neurological damage, such as long term functional impairment and disability. It has no cure and the symptoms vary widely, depending...
Diagnosis, Computer-Assisted Multiple Sclerosis, Relapsing-Remitting Humans Machine Learning Female Adult Male Disease Progression
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Acute hyperglycaemia in cystic fibrosis pulmonary exacerbations.

Endocrinology, diabetes & metabolism Nov 30, 2020
BACKGROUND: Hyperglycaemia may contribute to failure to recover from pulmonary exacerbations in cystic fibrosis (CF). We aimed to evaluate the prevalence and mechanism of hyperglycaemia during and post-exacerbations.
Monitoring, Physiologic Disease Progression Acute Disease Humans Prevalence Cystic Fibrosis Female Adolescent Glucose Tolerance Test Young Adult Child Insulin Secretion Male Hyperglycemia
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Machine learning algorithm for early detection of end-stage renal disease.

BMC nephrology Nov 27, 2020
BACKGROUND: End stage renal disease (ESRD) describes the most severe stage of chronic kidney disease (CKD), when patients need dialysis or renal transplant. There is often a delay in recognizing, diagnosing, and treating the various etiologies of CKD...
ROC Curve Logistic Models Renal Insufficiency, Chronic Predictive Value of Tests Kidney Failure, Chronic Female Male Middle Aged Disease Progression Humans Early Diagnosis Machine Learning Algorithms Databases, Factual Prognosis
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Discriminating pseudoprogression and true progression in diffuse infiltrating glioma using multi-parametric MRI data through deep learning.

Scientific reports Nov 23, 2020
Differentiating pseudoprogression from true tumor progression has become a significant challenge in follow-up of diffuse infiltrating gliomas, particularly high grade, which leads to a potential treatment delay for patients with early glioma recurren...
Oligodendroglioma Multiparametric Magnetic Resonance Imaging Adult Biopsy Brain Neoplasms Feasibility Studies Deep Learning Humans Male Neoplasm Recurrence, Local ROC Curve Retrospective Studies Middle Aged Data Accuracy Follow-Up Studies Female Disease Progression Astrocytoma Area Under Curve Aged
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Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research Nov 18, 2020
PURPOSE: Several biomarkers of response to immune checkpoint inhibitors (ICI) show potential but are not yet scalable to the clinic. We developed a pipeline that integrates deep learning on histology specimens with clinical data to predict ICI respon...
Humans Machine Learning Prospective Studies Prognosis Female Melanoma Skin Neoplasms Aged Neoplasm Staging Disease Progression Skin Adult ROC Curve Progression-Free Survival Male Immune Checkpoint Inhibitors Drug Resistance, Neoplasm Middle Aged Image Processing, Computer-Assisted Risk Assessment Follow-Up Studies
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Association of a Serum Protein Signature With Rheumatoid Arthritis Development.

Arthritis & rheumatology (Hoboken, N.J.) Nov 10, 2020
OBJECTIVE: The pathophysiologic events that precede the onset of rheumatoid arthritis (RA) remain incompletely understood. This study was undertaken to identify changes in the serum proteome that precede the onset of RA, with the aim of providing new...
Anti-Citrullinated Protein Antibodies Interleukin-1 Rheumatoid Factor Asymptomatic Diseases Lectins Calreticulin Toll-Like Receptor 2 Ficolins Adolescent Arthritis, Rheumatoid Proteomics Indians, North American Longitudinal Studies Adult Humans Male Middle Aged Machine Learning Disease Progression Tumor Necrosis Factor-alpha Female Aged Young Adult
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