AIMC Topic: Epithelial Cells

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Oral epithelial cell segmentation from fluorescent multichannel cytology images using deep learning.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Cytology is a proven, minimally-invasive cancer screening and surveillance strategy. Given the high incidence of oral cancer globally, there is a need to develop a point-of-care, automated, cytology-based screening tool. Or...

Uncovering additional predictors of urothelial carcinoma from voided urothelial cell clusters through a deep learning-based image preprocessing technique.

Cancer cytopathology
BACKGROUND: Urine cytology is commonly used as a screening test for high-grade urothelial carcinoma for patients with risk factors or hematuria and is an essential step in longitudinal monitoring of patients with previous bladder cancer history. Howe...

Automated annotations of epithelial cells and stroma in hematoxylin-eosin-stained whole-slide images using cytokeratin re-staining.

The journal of pathology. Clinical research
The diagnosis of solid tumors of epithelial origin (carcinomas) represents a major part of the workload in clinical histopathology. Carcinomas consist of malignant epithelial cells arranged in more or less cohesive clusters of variable size and shape...

Quick Annotator: an open-source digital pathology based rapid image annotation tool.

The journal of pathology. Clinical research
Image-based biomarker discovery typically requires accurate segmentation of histologic structures (e.g. cell nuclei, tubules, and epithelial regions) in digital pathology whole slide images (WSIs). Unfortunately, annotating each structure of interest...

A Classification Method for the Cellular Images Based on Active Learning and Cross-Modal Transfer Learning.

Sensors (Basel, Switzerland)
In computer-aided diagnosis (CAD) systems, the automatic classification of the different types of the human epithelial type 2 (HEp-2) cells represents one of the critical steps in the diagnosis procedure of autoimmune diseases. Most of the methods pr...

Machine-Learning-Based Approach to Decode the Influence of Nanomaterial Properties on Their Interaction with Cells.

ACS applied materials & interfaces
In an nanotoxicity system, cell-nanoparticle (NP) interaction leads to the surface adsorption, uptake, and changes into nuclei/cell phenotype and chemistry, as an indicator of oxidative stress, genotoxicity, and carcinogenicity. Different types of n...

Artificial Intelligence-Based Quantification of Epithelial Proliferation in Mammary Glands of Rats and Oviducts of Göttingen Minipigs.

Toxicologic pathology
Quantitative assessment of proliferation can be an important endpoint in toxicologic pathology. Traditionally, cell proliferation is quantified by labor-intensive manual counting of positive and negative cells after immunohistochemical staining for p...

Deep learning-based classification of the mouse estrous cycle stages.

Scientific reports
There is a rapidly growing demand for female animals in preclinical animal, and thus it is necessary to determine animals' estrous cycle stages from vaginal smear cytology. However, the determination of estrous stages requires extensive training, tak...

A Strictly Unsupervised Deep Learning Method for HEp-2 Cell Image Classification.

Sensors (Basel, Switzerland)
Classifying the images that portray the Human Epithelial cells of type 2 (HEp-2) represents one of the most important steps in the diagnosis procedure of autoimmune diseases. Performing this classification manually represents an extremely complicated...

Automated classification of cells into multiple classes in epithelial tissue of oral squamous cell carcinoma using transfer learning and convolutional neural network.

Neural networks : the official journal of the International Neural Network Society
The analysis of tissue of a tumor in the oral cavity is essential for the pathologist to ascertain its grading. Recent studies using biopsy images reveal computer-aided diagnosis for oral sub-mucous fibrosis (OSF) carried out using machine learning a...